Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Introduction: Celiac plexus radioablation (CPR) is an emerging non-invasive interventional treatment for severe pain associated with cancer-related damage to the celiac plexus. Due to its complex aetiology, such pain often responds poorly to conventional analgesics, and high doses of these medications can cause toxicity. Celiac plexus radiosurgery employs advanced radiotherapy techniques to administer a high single dose of 25 Gy to the anatomically defined celiac plexus, aiming to reduce pain intensity and enhance patients' quality of life.
Material And Methods: The safety and efficacy of CPR have been validated in a prospective single-arm clinical trial that included 125 patients.
Results: The positive outcomes of this trial led to the integration of CPR into pain management guidelines; however, the novel approach to radiotherapy planning might be initially challenging to grasp.
Conclusions: In this article, we provide a brief overview of the method along with a comprehensive, Polish and English-language guide on how to perform CPR and manage patients, based on our clinical experience.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538976 | PMC |
| http://dx.doi.org/10.5114/wo.2024.144315 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Endoscopic ultrasound-guided celiac plexus block for painful chronic pancreatitis: A systematic review and meta-analysis.
Pancreatology
August 2025
Digestive Health Institute, Orlando Health, Orlando, FL, USA. Electronic address:
Background: The efficacy of endoscopic ultrasound-guided celiac plexus block (EUS-CPB) for treatment of pain in chronic pancreatitis (CP) is unclear. Therefore, we aimed to assess this outcome using a systematic review and meta-analysis.
Methods: We conducted a comprehensive search of MEDLINE, EMBASE, and Cochrane Central for evaluating the efficacy of EUS-CPB for pain in CP.
Comparing Ultrasound and Computed Tomography in Regional Anesthesia: Real-Time Precision or Radiologic Clarity?
Cureus
July 2025
Surgery, Nishtar Medical University, Multan, PAK.
This systematic review evaluates the comparative effectiveness of ultrasound and computed tomography (CT) in guiding regional anesthesia, with a focus on block accuracy, anesthetic spread, clinical efficacy, and procedural safety. A total of seven high-quality clinical studies were included, encompassing a range of nerve blocks such as celiac plexus, interscalene, intertransverse, and erector spinae plane blocks. Ultrasound guidance consistently demonstrated outcomes that were equivalent or superior to CT guidance in terms of anesthetic distribution, pain control, and patient satisfaction.
View Article and Find Full Text PDFComparison of Different Spinal Level Approaches in Splanchnic Sympathetic Neurolysis for Intractable Upper Abdominal Cancer Pain: A Retrospective Review.
Pain Physician
July 2025
Department of Pain Medicine, University of Texas, MD Anderson Cancer Center, Houston, TX.
Background: Celiac plexus or splanchnic nerve neurolysis is a treatment modality commonly offered for cancer-related upper abdominal pain. The optimal spinal level for performing celiac/splanchnic sympathetic neurolysis remains unclear.
Objective: We aimed to assess the outcome, effectiveness, and complications associated with undergoing splanchnic sympathetic neurolysis at various spinal levels for treating intractable upper abdominal cancer pain.
Percutaneous Cryoneurolysis of Splanchnic Nerves for Pain Palliation in Patients with Pancreatic Cancer: A Single-Center Experience.
Cardiovasc Intervent Radiol
August 2025
2nd Department of Radiology, Medical School, University General Hospital "ATTIKON", National and Kapodistrian University of Athens, 1 Rimini Str, 12462, Haidari/Athens, Greece.
Purpose: To report safety and efficacy (on terms of long-term pain reduction results) after percutaneous splanchnic nerve cryoneurolysis for the treatment of refractory pancreatic cancer-related pain.
Materials And Methods: This single-center, institutional review board-approved, retrospective observational study recruited consecutive patients with pancreatic cancer-related pain refractory to conservative treatment who underwent CT-guided cryoneurolysis of the splanchnic nerves. Outcomes included overall pain reduction rate (> 4 pain score units in the VAS pain scores), technical success (successful cryoprobe placement at the level of interest), and opioid usage reduction.
Minimally invasive techniques versus opioids in patients with unresectable pancreatic cancer: a systematic review and meta-analysis of randomised controlled trials.
Transl Gastroenterol Hepatol
July 2025
Centre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Background: Pancreatic cancer (PC) has a low chance of resection, and a consistent burden of disease, with pain greatly impacting the quality of life (QoL). We aim to find the most efficient method to treat pain in patients with unresectable PC.
Methods: Our study was registered on PROSPERO (CRD42023477094).