98%
921
2 minutes
20
A growing number of humans have suffered severe chronic illnesses, which has caused a boost in the requirement for diagnostic and medical treatment procedures that are both accurate and fast. Improved patient conditions and enhanced Decision-Making Systems (DMS) for healthcare professionals are the primary objectives of the Clinical Decision Support System (CDSS) recommended in this research article. The main drawback of traditional Machine Learning (ML) techniques is their failure to predict reliably. To solve this problem, the proposed model creates an Ensemble Extreme Learning Machine (EN-ELM) algorithm that combines predictors trained on several different data sets. This lowers the chance of overfitting. The suggested CDSS uses many different data processing methods, including Adaptive Synthetic (ADASYN) and isolation Forest (iForest), which fix problems like outliers and class imbalance. This approach significantly enhances the framework's classification performance. Also, the CDSS is compatible with an EC model, which enables real-time computation while minimizing the requirement for integrated systems. The recommended CDSS applies iForest and ADASYN to execute large-scale trials validating high standards of accuracy across numerous datasets. Researchers concluded that a suitable ELM classification threshold of 85% is the most effective, which substantially boosts the accuracy of the predictive model. When applied to various medical datasets, such as Hepatocellular Carcinoma (HCC), Cervical Cancer, Chronic Kidney Disease (CKD), Heart Disease, and Arrhythmia, the EN-ELM achieved accuracy rates of 99.36%, 98.15%, 97.85%, 97.06%, and 96.72%, respectively. By measuring this progress, the CDSS could dramatically improve the accuracy of chronic illness diagnosis and treatment, which similarly affects clinicians.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11541999 | PMC |
http://dx.doi.org/10.1038/s41598-024-78225-5 | DOI Listing |
Front Microbiol
August 2025
Guangxi Key Laboratory of Aquatic Genetic Breeding and Healthy Aquaculture, Guangxi Academy of Fishery Science, Nanning, Guangxi, China.
A bacterial strain (No. 20230510) was isolated from the kidneys of diseased in Guangxi, China, since 2023. Artificial infection experiments demonstrated that this strain caused the observed disease in .
View Article and Find Full Text PDFMicrobiologyopen
October 2025
Department of Agronomy, National Taiwan University, Taipei, Taiwan.
Currently, there is an increasing use of whole-genome sequencing (WGS) studies to investigate the molecular taxonomy, metabolic properties, enzyme capabilities, and bioactive substances of lactic acid bacteria (LAB) species. In this study, the genome of strain Pediococcus pentosaceus BBS1 was sequenced using the Illumina HiSeq. 2500 platform to determine its classification, annotate its main features, and evaluate its safety characteristics.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
September 2025
Institute of Intelligent Machines, Chinese Academy of Science, Hefei, Anhui, P.R. China. Electronic address:
The convergence of artificial intelligence (AI) and wearable biosensors is revolutionizing personalized healthcare, enabling continuous monitoring, early detection of health issues, which enhances the efficiency of data processing and real-time decision-making. Multimodal Large Language Models (MLLMs) play a pivotal role in this ecosystem by offering advanced capabilities in analyzing complex health data, understanding nuanced health contexts, and generating tailored health recommendations instantaneously. This study provides insights into how machine learning, deep learning algorithms, and MLLM can work together to facilitate the analysis of physiologic data for real-time monitoring and early warning systems as well as complex decision support mechanisms.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
Key Laboratory of Veterinary Biotechnology, Guangxi Veterinary Research Institute, Nanning, Guangxi, China.
Unlabelled: Lactobacilli, recognized as beneficial bacteria within the human body, are celebrated for their multifaceted probiotic functions, including the regulation of intestinal flora, enhancement of body immunity, and promotion of nutrient absorption. This study comprehensively analyzed the genotypic and phenotypic characteristics of () strains isolated from the intestines of healthy chicks and assessed their potential as probiotics. The assembled genome consists of 29,521,986 bp, and a total of 1,771 coding sequences (CDSs) were predicted.
View Article and Find Full Text PDFFront Psychiatry
August 2025
TransLab Research Group, Department of Medical Sciences, University of Girona, Girona, Spain.
Introduction: Clinical practice guidelines (CPGs) have several limitations, namely: obsolescence, lack of personalization, and insufficient patient participation. These factors may contribute to suboptimal treatment recommendation compliance and poorer clinical outcomes. APPRAISE-RS is an adaptation of the GRADE heuristic designed to generate CPG-like treatment recommendations that are automated, updated, personalized, participatory, and explanatory using a symbolic AI approach.
View Article and Find Full Text PDF