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Article Abstract
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574616 | PMC |
| http://dx.doi.org/10.1093/europace/euae281 | DOI Listing |
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Atrial fibrillation and female sex: use of oral anticoagulants in a large European cohort and residual risk of thromboembolism and stroke.
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Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.
Background: The role of female sex in stroke risk and oral anticoagulant (OAC) use in atrial fibrillation (AF) remains controversial. This study evaluates sex-specific differences in OAC prescription, residual risk of stroke/TIA and thromboembolism (STE), and the predictive performance of CHA₂DS₂-VASc vs. CHA₂DS₂-VA scores.
View Article and Find Full Text PDFStroke Risk Stratification in Incident Atrial Fibrillation: A Sex-Specific Evaluation of CHA2DS2-VA and CHA2DS2-VASc.
J Cardiovasc Dev Dis
July 2025
Nursing Department, Advanced Nursing Research Group at Rovira i Virgili University, Biomedicine Doctoral Programme Campus Terres de l'Ebre, Av. De Remolins, 13, 43500 Tortosa, Spain.
(1) Background: In the absence of locally validated tools, the CHA2DS2-VA score has been suggested as a substitute for the CHA2DS2-VASc score. This study compared the potential discrepancies between these scores. (2) Methods: The observational, retrospective, and community-based study included a cohort of 3370 patients with a new diagnosis of atrial fibrillation (AF) between 1 January 2015 and 31 December 2024.
View Article and Find Full Text PDFPredictive Value of RCHADS-VA Score for 90-Day Functional Outcomes After Endovascular Thrombectomy in Acute Ischemic Stroke.
Medicina (Kaunas)
May 2025
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: Endovascular treatment (EVT) has been shown to enhance long-term recovery and lower mortality rates in patients with intracranial large vessel occlusion-associated acute ischemic strokes (AISs).We aimed to evaluate the predictive value of the pre-stroke CHADS-VA, RCHADS-VA, CHADS-VASc, and RCHADS-VASc scores in determining 90-day functional outcomes based on the modified Rankin Scale (mRS). : In a single center between 2018 and 2023, 665 AIS patients who underwent EVT and achieved successful reperfusion were screened retrospectively.
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Eur Heart J Cardiovasc Pharmacother
August 2025
Liverpool Centre for Cardiovascular Sciences at University of Liverpool, Liverpool John Moors University and Liverpool Heart & Chest Hospital, Liverpool L7 8TX, UK.
Aims: Whether the adoption of CHA2DS2-VA score, the sex-independent version of the CHA2DS2-VASc score is beneficial for stratifying risk of stroke in patients with atrial fibrillation (AF) remains controversial.
Methods And Results: Utilizing the data from the global, multicentre and prospective GLORIA-AF Registry Phase III, we compared the performances of CHA2DS2-VA and CHA2DS2-VASc scores in stratifying the risk of ischaemic stroke and thromboembolism (TE), and compared the risk of ischaemic stroke and TE, and the use of oral anticoagulants in male and female patients with AF. A total of 21 260 AF patients with available data were included in the analysis (mean age 70.
The association between whole blood viscosity and CHA2DS2-VASc/CHA2DS2-VA scores in patients with atrial fibrillation.
Future Sci OA
December 2025
Department of Cardiology, Health Sciences University, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey.
Introduction: CHA2DS2-VASc and CHA2DS2-VA scores are often used to demonstrate thromboembolic risk in nonvalvular atrial fibrillation. Elevated whole blood viscosity is an independent risk factor for ischemic stroke.
Objective: This study aimed to ascertain the correlation between whole blood viscosity and CHA2DS2-VASc/CHA2DS2-VA scores.