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Faricier, R, Fleitas-Paniagua, PR, Iannetta, D, Millet, GY, Keir, DA, and Murias, JM. Time spent near maximal oxygen uptake during exercise at different regions of the severe-intensity domain. J Strength Cond Res 39(2): e106-e114, 2025-This study applied the critical power (CP) model and several bouts of constant-power exercise within different regions of the severe-intensity domain to determine whether there exists an optimal intensity to maximize time spent near V̇ o2 peak. Subjects visited the laboratory 9 times. After a ramp-incremental test to determine V̇ o2 peak and peak power output (PO peak ), 9 active individuals (5 females) performed 4 constant-power bouts to task failure between 65 and 100%PO peak to estimate CP and total finite work above CP (W'). Subjects then completed 4 additional exhaustive trials predicted to result in task failure in ∼3, 6, 9, and 12 minutes. Time spent at V̇ o2 peak was calculated as the duration at which V̇ o2 ≥ 95% of the trial-specific V̇ o2 peak. The level of significance set for the study was p < 0.05. Mean CP and W' were 201 ± 48 W and 17.6 ± 8.4 kJ, respectively. For each bout, time to task failure was 2.7 ± 0.5, 6.3 ± 0.6, 9.5 ± 1.2, and 13.1 ± 3.1 minutes for the 3-, 6-, 9-, and 12-minute conditions. Time spent at V̇ o2 peak during the 3-minute trial (45 ± 22 seconds) was shorter than during the 9-minute (204 ± 104 seconds; p = 0.002) and 12-minute trials (260 ± 155 seconds; p < 0.001). The 6-minute trial (117 ± 46 seconds) had shorter ( p = 0.005) time spent at V̇ o2 peak compared with the 12-minute trial. At least when performing single bouts of exercise, intensities closer to CP (i.e., those sustainable for ∼9 minutes or longer) seem preferable compared with POs in the upper regions of the severe-intensity domain to maximize time at V̇ o2 peak.
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http://dx.doi.org/10.1519/JSC.0000000000004986 | DOI Listing |
Psychophysiology
June 2025
Graduate School of Human Sciences, The University of Osaka, Osaka, Japan.
It is thought that our brains actively predict what will happen next in the environment, but it remains unclear how specific the prediction of an upcoming event is. This study investigated whether the prediction about the sensory modality of the upcoming stimulus modulates neural responses to unexpected omissions of stimuli. Previous research has reported that the peak latencies of omitted stimulus potentials (OSPs) are shorter in the auditory modality than in the visual modality when tested in separate blocks.
View Article and Find Full Text PDFJ Chromatogr A
August 2025
Department of Chemical, Material & Regulatory Science, BASF SE, Carl-Bosch-Str. 38, 67056 Ludwigshafen am Rhein, Germany. Electronic address:
This study presents the separation of vitamin A acetate (VAA) and other retinoids, as well as their respective stereoisomeric forms, with the help of supercritical fluid chromatography (SFC). The basis for this was a method of reversed-phase high-performance liquid chromatography (HPLC), presented by Schräder et al. (2024).
View Article and Find Full Text PDFMatrix Biol
August 2022
Department of Diagnostic & Biomedical Sciences, University of Texas Health Science Center at Houston School of Dentistry, 1941 East Road, BBS-4220, Houston, TX 77054, USA.; Departments of BioSciences and Bioengineering, Rice University, 6100 Main St., Houston, TX 77005, USA.; Center for Theoretical
The extracellular matrix (ECM) is a highly dynamic, well-organized acellular network of tissue-specific biomolecules, that can be divided into structural or core ECM proteins and ECM-associated proteins. The ECM serves as a blueprint for organ development and function and, when structurally altered through mutation, altered expression, or degradation, can lead to debilitating syndromes that often affect one tissue more than another. Cross-referencing the FANTOM5 SSTAR (Semantic catalog of Samples, Transcription initiation And Regulators) and the defined catalog of core matrisome ECM (glyco)proteins, we conducted a comprehensive analysis of 511 different human samples to annotate the context-specific transcription of the individual components of the defined matrisome.
View Article and Find Full Text PDFRadiology
June 2022
From the Departments of Radiology (O.O.K., V.A.A., O.O.A.) and Pediatrics (O.A.), Obafemi Awolowo University Teaching Hospitals Complex, PMB 5538, Ilesa Rd, Ile-Ife 220212, Nigeria; and Department of Radiology, Afe Babalola University, Ado-Ekiti, Nigeria (C.O.).
Background Children with sickle cell anemia (SCA) are predisposed to developing leg ulcers in early adolescence; however, the underlying physiologic mechanisms are not well understood, which hinders the development of prophylactic antiulcer interventions. Purpose To determine if occlusive arterial disease or abnormal hemodynamics exist in the lower limb peripheral arteries of children with SCA. Materials and Methods This was a prospective cross-sectional study conducted between July 2020 and May 2021.
View Article and Find Full Text PDFMol Immunol
June 2021
Laboratory of Pathology and Immunology of Aquatic Animals, KLMME, Ocean University of China, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, No. 1 Wenhai Road, Aoshanwei Town, Qingdao 266071, China. Electron
The efficacy of DNA vaccine is associated closely with the expression of the antigen and the intensity of local immune responses. In our previous study, a recombinant DNA plasmid expressing the VAA protein (pVAA) of Listonella anguillarum has been proved to have a good protection against the infection of L. anguillarum.
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