98%
921
2 minutes
20
A 55-year-old woman presented with an incidental finding of significant respiratory variation in mean right atrial pressure during cardiac catheterization. Later, she was evaluated and diagnosed with sleep apnea. A significant increase in right atrial pressure with respiration should raise awareness for sleep apnea.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522803 | PMC |
http://dx.doi.org/10.1016/j.jaccas.2024.102567 | DOI Listing |
JACC Cardiovasc Imaging
September 2025
Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium; Faculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium. Electronic address:
Background: Atrial functional mitral regurgitation (AFMR) is prevalent among patients with heart failure with preserved ejection fraction (HFpEF) and associated with adverse outcome, yet this bidirectional association remains underexplored.
Objectives: The purpose of this study was to elucidate the pathophysiological and prognostic significance of AFMR in HFpEF, both at rest and during exercise.
Methods: In this multicenter cohort study, consecutive patients with HFpEF underwent cardiopulmonary exercise testing with echocardiography, with a particular focus on mitral regurgitation (MR) severity assessment in rest and during exercise.
Int J Cardiol
September 2025
Department of Cardiovascular Surgery, State Key Laboratory of Frigid Zone Cardiovascular Disease, General Hospital of Northern Theater Command, Shenyang 110016, China. Electronic address:
Background: Atrial fibrillation and flutter (AF/AFL) are traditionally regarded as diseases of ageing, with most research focused on elderly populations. In contrast, early-onset AF/AFL (<65 years) is increasingly recognized as a potential marker of cardiomyopathy, yet its global burden remains poorly understood.
Methods: Using data from the Global Burden of Disease 2021 study, we analyzed trends in prevalence, incidence, disability-adjusted life years (DALYs), mortality, and average annual percentage change (AAPC) of AF/AFL among individuals aged 30-64 years from 1990 to 2021.
J Inflamm Res
August 2025
Department of Neurology II, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710068, People's Republic of China.
Objective: Large hemispheric infarction (LHI) represents one of the most severe subtypes of ischemic stroke, associated with high rates of disability and mortality. This study aimed to examine the association between the systemic inflammation response index (SIRI) and LHI, identify independent risk factors, and develop a predictive model for clinical application.
Methods: A total of 152 patients diagnosed with LHI and admitted to Shaanxi Provincial People's Hospital between June 2020 and June 2023 were retrospectively selected based on defined inclusion and exclusion criteria.
Eur J Heart Fail
September 2025
Brazilian Clinical Research Institute (BCRI), São Paulo, Brazil.
Aims: The PARACHUTE-HF trial (NCT04023227) is evaluating the effect of sacubitril/valsartan compared with enalapril on a hierarchical composite of cardiovascular events (cardiovascular death, first heart failure hospitalization), and change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in participants with heart failure and reduced ejection fraction (HFrEF) caused by chronic Chagas cardiomyopathy (CCC). We describe the baseline characteristics of participants in PARACHUTE-HF compared with prior HFrEF trials.
Methods And Results: PARACHUTE-HF, a multicentre, active-controlled, open-label trial, enrolled 922 participants with confirmed CCC, New York Heart Association (NYHA) functional class II-IV, and left ventricular ejection fraction (LVEF) ≤40%.
J Cardiol
September 2025
Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Department of Epidemiology, Disease Control, and Prevention, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan. Electronic address:
Background: Guidelines recommend biomarker-based screening for pre-heart failure (pre-HF) among at-risk populations. Although the asymptomatic nature of pre-HF necessitates proactive screening, real-world implementation remains understudied. This retrospective study analyzed data from a regional pre-HF screening initiative, integrated into annual health screenings, to evaluate: (1) the prevalence of elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels, (2) associated echocardiographic findings, and (3) adherence across the screening-to-consultation pathway.
View Article and Find Full Text PDF