J Sci Med Sport
August 2025
Four ultra-endurance athletes (3M/1F) navigated ~800 km via trekking, biking, and paddling using topographical maps and compass, sleeping ~6 h each. Mood, cognitive performance, and heart rate variability were measured at baseline (PRE), post-race (POST), and 18-h post-race (POST18). Decreased anxiety (ΔMdn = 6.
View Article and Find Full Text PDFBehav Pharmacol
August 2025
Cannabidiol (CBD) is a phytocannabinoid without intoxicating properties. While CBD can improve neurophysiological functions and subjective symptoms, its effect on cognitive function remains unclear. We summarized the available randomized controlled trials investigating CBD administration and cognitive function.
View Article and Find Full Text PDFParkinson's disease (PD) has become the second most prominent neurogenerative disorder relating to aging individuals. PD involves the loss of neurons containing dopamine in the midbrain and leads to a number of motor issues as well as non-motor complications such as cognitive and psychological abnormalities. The default mode network (DMN) is a complex brain network primarily active during rest and serves multiple roles relating to memory, self-referential processing, social cognition and consciousness and awareness.
View Article and Find Full Text PDFBackground: Using functional near-infrared spectroscopy (fNIRS) as an objective diagnostic tool, we aimed to (1) compare fNIRS measurements in adult and youth male rugby players against controls over a playing season, and 2) document the fNIRS changes that occur in concussed rugby players during the England Rugby Football Union Graduated Return-To-Play programme (GRTP). Sixty-seven participants (rugby = 41 (26 adults: 27.5 ± 4.
View Article and Find Full Text PDFObjective: Transradial cardiac catheterization has gained popularity because of its reduced risk of access-site complications, yet procedural failures remain frequent, often caused by subclavian artery tortuosity. We propose an alternative maneuver to improve procedural success rates, addressing the challenge of subclavian artery tortuosity more efficiently than existing time-consuming and resource-intensive techniques.
Key Steps: Place a towel between the patient's scapulae to retract the shoulders before advancing the catheter.
BMJ Open Sport Exerc Med
March 2025
There are limited therapeutic options for patients with persistent postconcussive symptoms (PPCSs). Most PPCS assessments focus on subjective measures of progression and symptom monitoring. While early exercise interventions for rehabilitation are now considered best practice for acute concussion, no comprehensive review exists on how physical activity objectively and physiologically affects outcomes in PPCS.
View Article and Find Full Text PDFHemodynamic parameters are frequently used in patients with cardiovascular disease to assess cardiac function, monitor disease progression, propose interventions, and determine prognosis. However, they require extensive resources, including specialized equipment and trained personnel, to measure with accuracy and precision. Wearable devices such as wristwatches have been shown to assess heart function, such as heart rate and detection of irregular heart rhythms.
View Article and Find Full Text PDFAssessment of cerebral oxygenation during repeated squat stands following an acute sport-related concussion (SRC) has the potential to identify physiological changes following SRC. All varsity university athletes completed a pre-season assessment and 53 were followed up within 5-days of suffering an SRC. Of the 53 participants, 29 had continuous beat-to-beat blood pressure (BP; sampled at 200 hz) collected by finger photoplethysmography, and 53 had right prefrontal cortex oxygenation collected by near-infrared spectroscopy (NIRS; sampled at 10 hz).
View Article and Find Full Text PDFJACC Case Rep
October 2024
A 55-year-old woman presented with an incidental finding of significant respiratory variation in mean right atrial pressure during cardiac catheterization. Later, she was evaluated and diagnosed with sleep apnea. A significant increase in right atrial pressure with respiration should raise awareness for sleep apnea.
View Article and Find Full Text PDFAppl Physiol Nutr Metab
January 2025
Background: Cannabinoids such as cannabidiol (CBD) exhibit anti-inflammatory properties and have the potential to act as a therapeutic following mild traumatic brain injury. There is limited evidence available on the pharmacological, physiological and psychological effects of escalating CBD dosages in a healthy, male, university athlete population. Furthermore, no dosing regimen for CBD is available with implications of improving physiological function.
View Article and Find Full Text PDFThere is still much uncertainty surrounding the approach to diagnosing and managing a sport-related concussion (SRC). Neurobiological recovery may extend beyond clinical recovery following SRC, highlighting the need for objective physiological parameters to guide diagnosis and management. With an increased understanding of the connection between the heart and the brain, the utility of assessing cardiovascular functioning following SRC has gained attention.
View Article and Find Full Text PDFSport-related concussion (SRC) is known to disrupt neurohemodynamic activity, cardiac function, and blood pressure (BP) autoregulation. This study aims to observe changes in cerebrovascular and cardiovascular responses during controlled respiration after sustaining an SRC. University varsity athletes ( = 81) completed a preseason physiological assessment and were followed up within 5 days of sustaining an SRC.
View Article and Find Full Text PDFThe growing incidence of Parkinson's Disease (PD) is a major burden on the healthcare system. PD is caused by the degeneration of dopaminergic neurons and is known for its effects on motor function and sleep. Sleep is vital for maintaining proper homeostasis and clearing the brain of metabolic waste.
View Article and Find Full Text PDFThis exploratory study aimed to investigate the long-term effects of multiple concussions on prefrontal cortex oxygenation during a five-minute hypercapnic challenge using Near Infrared Spectroscopy (NIRS). 55 physically active retired contact sport male athletes with three or more previous concussions (mTBI) were recruited along with 29 physically active males with no concussions history (CTRL). Participants completed five minutes of seated rest prior to the five-minute hypercapnic challenge (20-second breath-hold, 40-second recovery breathing; five times).
View Article and Find Full Text PDFHealth Promot Chronic Dis Prev Can
November 2023
Introduction: Posttraumatic stress disorder (PTSD) can induce an elevation in sympathetic tone; however, research pertaining to the cardiac cycle in patients with PTSD is limited.
Methods: A literature review was conducted with PubMed, MEDLINE and Web of Science. Articles discussing changes and associations in echocardiography and PTSD or related symptoms were synthesized for the current review.
Women experience greater difficulties in quitting smoking than men, though the hormonal factors contributing to this sex difference remain to be clarified. The current study aimed to examine menstrual cycle effects on smoking cue-induced cravings as well as examine dynamic reproductive hormone change as a potential mediator underlying any cycle effects observed. Twenty-one women who smoke underwent two laboratory sessions - one in the mid-follicular phase and the other in the late luteal phase - involving an in-vivo smoking cue task, administered before and after exposure to a psychosocial laboratory stressor.
View Article and Find Full Text PDFHeart rate variability (HRV), systolic blood pressure variability (BPV), and spontaneous baroreflex sensitivity (BRS) are indirect and approximate measures of autonomic regulation of the cardiovascular system. Studies have shown differences in HRV and BRS between males and females; however, no study has observed differences in BPV, HRV, or BRS between male and female athletes. One hundred males (age 21.
View Article and Find Full Text PDF