Liver DE(HP)toxification: luteolin as "phthalates-cleaner" to protect from environmental pollution.

EMBO Mol Med

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

Published: November 2024


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Article Abstract

Environmental pollution is a major health problem that affects the health of individuals worldwide and is cumulative with other environmental stressors, contributing to the increasing prevalence of cancer, cardiometabolic, neurological and autoimmune diseases (Favé et al, 2018). Although being extensively studied, therapeutic strategies still rely primarily on exposure prevention, often with no option available to allow pollutant detoxification. In this issue of , Wang et al (Wang et al, 2024) investigated potential pharmacological strategies to allow the direct removal of phthalates, major environmental pollutants, from the liver.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11554642PMC
http://dx.doi.org/10.1038/s44321-024-00158-3DOI Listing

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