Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489641 | PMC |
| http://dx.doi.org/10.34172/jcvtr.33164 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Breast Tissue Reconstruction Strategies: A Tissue Engineering Approach.
Tissue Eng Part B Rev
September 2025
Latner Thoracic Research Laboratories, Division of Thoracic Surgery, Toronto General Hospital Research Institute, University Health Network, Toronto, Ontario, Canada.
Breast cancer remains the most commonly diagnosed malignancy among women worldwide. Standard treatment often involves mastectomy, followed by chemotherapy and/or radiation. Approximately 40% of patients undergo breast reconstruction to address the physical and psychological effects of tissue loss.
View Article and Find Full Text PDFUltrasound-optimized decellularization and functional modification for enhanced vascular grafts.
Biofabrication
September 2025
Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing 100048, People's Republic of China.
This study aimed to improve the efficiency of decellularization and enhance the functional properties of vascular grafts to optimize their application in vascular repair. Rabbit abdominal aortas were used as the decellularization target, and ultrasound-assisted decellularization was performed using intermittent ultrasound at 100 W power, 20 kHz frequency, and 4 °C. Rabbit abdominal aortas were subjected to three different decellularization techniques.
View Article and Find Full Text PDFEngineering the Future of Stem Cells in Vascular Reconstruction: A Leap Towards Functional Endothelialized Tissue-Engineered Vascular Conduits.
Stem Cell Rev Rep
September 2025
Paris Cité University, INSERM UMR-S 970, Paris Cardiovascular Research Centre, Paris, France.
The transition from reconstructive to regenerative strategies in vascular surgery has intensified the need for grafts that are biocompatible, growth-capable, and resistant to thrombosis. Addressing this challenge, Park et al. introduce a groundbreaking method for engineering fully biological, endothelialized tissue-engineered vascular conduits (TEVCs) using decellularized human umbilical arteries (dHUAs) coated with human induced pluripotent stem cell-derived endothelial cells (hiPSC-ECs).
View Article and Find Full Text PDFRecellularization of decellularized vascular grafts via aligned seeding of endothelial cells derived from human iPS cells.
Sci Rep
September 2025
Laboratory for Biomaterials and Bioengineering, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan.
The development of decellularized vascular tissues for tissue engineering and vascular implants presents a promising approach to creating functional blood vessels. However, effective endothelialization with human endothelial cells remains challenging. This study examined the endothelialization of decellularized porcine aortas using human induced pluripotent stem (hiPS) cell-derived endothelial cells.
View Article and Find Full Text PDFFabrication and characterization of electrospun polycaprolactone/ derived-ECM composite scaffolds for small-diameter vascular grafts.
RSC Adv
August 2025
Department of Biotechnology and Bioinformatics, Korea University Sejong 30019 Republic of Korea +82-44-860-1414.
Small-diameter vascular grafts (SDVGs; ≤6 mm inner diameter) often fail due to thrombosis, poor endothelialization, and low patency. To overcome these limitations, we developed electrospun composite scaffolds incorporating decellularized ECM (UdECM), a marine invertebrate source rich in collagen, glycosaminoglycans, and elastin. UdECM was blended with polycaprolactone (PCL) at 1, 5, and 10 wt% and electrospun into fibrous matrices.
View Article and Find Full Text PDF