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With the development of deep learning, the unsupervised visual anomaly detection and localization task has gained significant attention in both academia and industry, where only normal data are used for training. Existing methods for this task typically train using all training data simultaneously. However, in practical industrial scenarios, new product classes are usually introduced incrementally, leading to the sequential availability of training data. Such scenarios demand methods for class-incremental anomaly detection and localization (CADL). The main challenge of class-incremental learning is to retain knowledge of old classes when learning new classes. In this article, we aim to effectively leverage limited exemplars of old classes to retain knowledge for the CADL task. Achieving this goal requires a model that can efficiently capture anomaly-identification-related knowledge from limited exemplars. Considering that pixel-level anomaly identification requires an understanding of the surrounding context, we treat context within inputs as valuable anomaly-identification-related knowledge and design a context-aware feature reconstruction (CFR) model to capture such knowledge. Moreover, to avoid inter-class context conflict that may arise with class increments, we design an intermediate feature organization strategy. This strategy and output-level knowledge distillation jointly form dual constraints to regularize the model at both mid-feature and output levels. Utilizing the CFR model with Dual Constraints, the proposed CFRDC can effectively retain old-class knowledge while learning new classes, thus addressing the CADL task. Experimental results on the commonly-used MVTec-AD dataset demonstrate the effectiveness and outstanding performance of the proposed method in CADL.
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http://dx.doi.org/10.1016/j.neunet.2024.106788 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Urology, Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Background: Circumcision is a widely practiced procedure with cultural and medical significance. However, certain penile abnormalities-such as hypospadias or webbed penis-may contraindicate the procedure and require specialized care. In low-resource settings, limited access to pediatric urologists often leads to missed or delayed diagnoses.
View Article and Find Full Text PDFRev Bras Enferm
September 2025
Federal University of Ceará. Fortaleza, Ceará, Brazil.
Objective: to analyze predictors of inadequacy of prenatal care among postpartum women in a maternity hospital in Brazil.
Methods: cross-sectional study conducted from March 2020 to January 2021 with postpartum women from a maternity hospital in Brazil. Statistical analysis was performed using Pearson's chi-squared test and Poisson regression.
JAMA Cardiol
September 2025
Department of Cardiology, Inselspital University Hospital of Bern, University of Bern, Bern, Switzerland.
Importance: Right anomalous aortic origin of a coronary artery (R-AAOCA) is a rare congenital condition increasingly diagnosed with the growing use of cardiac imaging. Due to dynamic compression of the anomalous vessel, invasive fractional flow reserve (FFR) during a dobutamine-atropine volume challenge (FFR-dobutamine) is considered the reference standard. A reliable alternative method is needed to reduce extensive invasive testing, but it remains uncertain whether noninvasive imaging can accurately assess the hemodynamic relevance of R-AAOCA.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Cytogenetics and Molecular Genetics Lab, Pathology Unit, Medical Division (BARC Hospital), Bhabha Atomic Research Centre, Anushakti Nagar, Mumbai, India.
Background: Hearing loss (HL) is one of the most common congenital anomalies and is a complex etiologically diverse condition. Molecular genetic characterization of HL remains challenging owing to the high genetic heterogeneity. This study aimed to screen for potential disease-causing genetic variations in a cohort of Indian patients with congenital bilateral severe-to-profound sensorineural HL.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol
September 2025
Children's Hospital of Michigan, Division of Hematology/Oncology.
Glanzmann thrombasthenia (GT) is a rare autosomal recessive platelet disorder characterized by abnormalities in platelet aggregation, resulting from quantitative or qualitative defects in integrins αIIb and β3. Currently, allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only potentially curative therapeutic approach for severe GT. In this report, we present 2 children with GT that underwent successful allo-HSCT, along with 2008 to 2022 data from the Center for International Blood and Marrow Transplant Research and a summary of the existing literature providing further evidence that allo-HSCT can be a curative approach that prevents severe and life-threatening bleeding in GT.
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