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Background: Reaching meaningful interoperability between proprietary health care systems is a ubiquitous task in medical informatics, where communication servers are traditionally used for referring and transforming data from the source to target systems. The Mirth Connect Server, an open-source communication server, offers, in addition to the exchange functionality, functions for simultaneous manipulation of data. The standard Fast Healthcare Interoperability Resources (FHIR) has recently become increasingly prevalent in national health care systems. FHIR specifies its own standardized mechanisms for transforming data structures using StructureMaps and the FHIR mapping language (FML).
Objective: In this study, a generic approach is developed, which allows for the application of declarative mapping rules defined using FML in an exchangeable manner. A transformation engine is required to execute the mapping rules.
Methods: FHIR natively defines resources to support the conversion of instance data, such as an FHIR StructureMap. This resource encodes all information required to transform data from a source system to a target system. In our approach, this information is defined in an implementation-independent manner using FML. Once the mapping has been defined, executable Mirth channels are automatically generated from the resources containing the mapping in JavaScript format. These channels can then be deployed to the Mirth Connect Server.
Results: The resulting tool is called FML2Mirth, a Java-based transformer that derives Mirth channels from detailed declarative mapping rules based on the underlying StructureMaps. Implementation of the translate functionality is provided by the integration of a terminology server, and to achieve conformity with existing profiles, validation via the FHIR validator is built in. The system was evaluated for its practical use by transforming Labordatenträger version 2 (LDTv.2) laboratory results into Medical Information Object (Medizinisches Informationsobjekt) laboratory reports in accordance with the National Association of Statutory Health Insurance Physicians' specifications and into the HL7 (Health Level Seven) Europe Laboratory Report. The system could generate complex structures, but LDTv.2 lacks some information to fully comply with the specification.
Conclusions: The tool for the auto-generation of Mirth channels was successfully presented. Our tests reveal the feasibility of using the complex structures of the mapping language in combination with a terminology server to transform instance data. Although the Mirth Server and the FHIR are well established in medical informatics, the combination offers space for more research, especially with regard to FML. Simultaneously, it can be stated that the mapping language still has implementation-related shortcomings that can be compensated by Mirth Connect as a base technology.
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http://dx.doi.org/10.2196/57569 | DOI Listing |
MedEdPublish (2016)
May 2025
Newcastle University Faculty of Medical Sciences, Newcastle upon Tyne, England, UK.
Background: Whilst debriefing literature offers valuable tools for healthcare education, there remains a gap in resources specifically designed for debriefing communication skills. Effective communication is fundamental to patient care, particularly during sensitive interactions. This article provides a specialised toolkit for educators to enhance communication skills debriefing, developed through synthesis of existing literature and the authors' extensive experience teaching communication skills through simulation.
View Article and Find Full Text PDFCommun Biol
September 2025
Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, UK.
Primate lateral intraparietal area (LIP) has been directly linked to perceptual categorization and decision-making. However, the intrinsic LIP circuitry that gives rise to the flexible generation of motor responses to sensory instruction remains unclear. Using retrograde tracers, we delineate two distinct operational compartments based on different intrinsic connectivity patterns of dorsal and ventral LIP.
View Article and Find Full Text PDFJ Aging Stud
September 2025
Universitat de Lleida, Department of Foreign Languages and Literatures, Pl. Víctor Siurana, 1, 25003 Lleida, Spain. Electronic address:
Despite having published seventeen novels, a good number of short stories, and scripts since she started her writing career at the end of the 1970s, academic work on Moggach's literary career has mainly dealt with her novel These Foolish Things (2004) and its film version The Best Exotic Marigold Hotel (2011). This paper will focus on Moggach's last three novels in which the reader is guided by the voice of three women in their late sixties and seventies, namely Something to Hide (2015), The Carer (2019), and The Black Dress (2021). Following an already well-established body of criticism on representations of female ageing in fiction, this paper will argue that Moggach's last novels add nuance and richness to the representation of female ageing in the twenty-first century.
View Article and Find Full Text PDFVaccine
September 2025
Sydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia; Sydney Infectious Diseases Institute, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia. Electronic address:
Background/objectives: The importance of pro-equity strategies in addressing disadvantages that people and communities face due to their gender, migration status, ethnicity, disability, and place of residence is increasingly being recognised, but analysis of empirical evidence on how they improve vaccination in these priority groups is limited. This systematic review aims to fill this gap.
Methods: Standard evidence synthesis methods were employed, with searches conducted in four major bibliographic databases in March 2025.
Cereb Cortex
August 2025
Faculty of Psychology and Education Science, Department of Psychology, University of Geneva, Chemin des Mines 9, Geneva, 1202, Switzerland.
Language learning and use relies on domain-specific, domain-general cognitive and sensory-motor functions. Using fMRI during story listening and behavioral tests, we investigated brain-behavior associations between linguistic and non-linguistic measures in individuals with varied multilingual experience and reading skills, including typical reading participants (TRs) and dyslexic readers (DRs). Partial Least Square Correlation revealed a main component linking cognitive, linguistic, and phonological measures to amodal/associative brain areas.
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