Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Objective: To evaluate the availability and reliability of the European League Against Rheumatisms Outcome Measures in Rheumatology Synovitis (EULAR-OMERACT) scoring system among radiologists with different levels of musculoskeletal ultrasound (US) experience in assessing synovitis in patients with rheumatoid arthritis (RA).

Method: The patients with RA were retrospectively recruited from January 2020 to March 2022. Five radiologists with different levels of US experience were recruited for the reader study (R1-5), which included two parts. The participating radiologists first read 120 gray-scale (GS) and 120 Doppler US images twice, before and after a standard training program. In the first part, they semi-quantitatively scored the images from 0 to 3 based on the EULAR-OMERACT scoring system. In the second part, they read and scored 165 paired GS and Doppler images two times in 1 month using the EULAR-OMERACT scoring system. The correlation between the sum of the GSUS and power Doppler US (PDUS) image scores and the clinical scores was assessed.

Result: The intra-rater agreement of the five radiologists was good for the EULAR-OMERACT scoring system, with κ ranging from 0.72 to 0.94 for GSUS and from 0.81 to 0.97 for PDUS. The inter-rater agreement among the experts was good to very good in the EULAR-OMERACT scoring system (κ: 0.76-0.94 for GSUS and 0.80-0.96 for PDUS). The sum of the GSUS and PDUS scores in the EULAR-OMERACT scoring system was moderate to highly positively correlated with the clinical scores (ρ of GSUS: 0.58-0.79, ρ of PDUS: 0.57-0.70 for disease activity score in 28 joints C-reactive protein) after training.

Conclusion: The EULAR-OMERACT scoring system is a reliable method for evaluating synovitis in RA and shows potential for disease assessment and follow-up in patients with RA.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11719759PMC
http://dx.doi.org/10.1002/jum.16607DOI Listing

Publication Analysis

Top Keywords

eular-omeract scoring
32
scoring system
32
eular-omeract
8
scoring
8
system
8
radiologists levels
8
doppler images
8
sum gsus
8
clinical scores
8
good eular-omeract
8

Similar Publications

Imaging Neoangiogenesis in Rheumatoid Arthritis (INIRA) Part II: Whole-body Synovial Uptake of Tc-maraciclatide is Highly Correlated with Power Doppler Ultrasound.

Acad Radiol

August 2025

Department of Rheumatology, Guy's and St Thomas' NHS Foundation Trust, Great Maze Pond, London SE1 9RT, UK (L.A., S.S., C.B-G., M.O., S.N., A.P.C., T.G.).

Rationale And Objectives: Ultrasound (US) and MRI are more sensitive than clinical examination in detecting synovitis in patients with rheumatoid arthritis (RA). It is impractical however to image large numbers of joints in routine settings. Tc-maraciclatide is a radio-labeled small molecule tracer which binds with high affinity to integrin αvβ3, a cell-adhesion molecule up-regulated on neoangiogenic blood vessels, and therefore has the potential to image synovial inflammation at the whole-body level.

View Article and Find Full Text PDF

: In recent years, musculoskeletal ultrasonography (MSUS) has established itself as a reliable method for evaluating disease activity in combination with clinical examination and laboratory tests. : In this pilot study, we aimed to evaluate the ultrasound response to treatment with tofacitinib and upadacitinib on tendons and joints in comparison to clinical and laboratory results in patients with RA who have shown inadequate response to conventional synthetic and/or biologic disease-modifying antirheumatic drugs (cs/b DMARDs). : This study presents the MSUS assessment of therapeutic response in RA patients treated with tofacitinib or upadacitinib over a 24-week period.

View Article and Find Full Text PDF

Objective: Patient-level ultrasound joint inflammation outcomes, derived from the European Alliance of Associations for Rheumatology-Outcome Measures in Rheumatology (EULAR-OMERACT) joint-level scoring of elementary components and the combined score (CS), were compared with measures of disease activity and joint damage in patients with rheumatoid arthritis (RA).

Methods: Clinical joint assessment and a 22-joint (bilateral hands/wrists) ultrasonography were performed independently during the same patient study visit. Patient-level ultrasound joint inflammation outcomes [total power Doppler (PD) score, total grayscale (GS) score, total CS, number of joint(s) with CS ≥ 2 (at least moderate synovitis), and number of joint(s) with ultrasound synovitis defined as PD > 0 or GS ≥ 2] derived from the EULAR-OMERACT joint-level scoring system were correlated with Clinical Disease Activity Index (CDAI), 28-joint disease activity score (DAS28), and ultrasound-detected joint damage, i.

View Article and Find Full Text PDF

Objective: To evaluate the availability and reliability of the European League Against Rheumatisms Outcome Measures in Rheumatology Synovitis (EULAR-OMERACT) scoring system among radiologists with different levels of musculoskeletal ultrasound (US) experience in assessing synovitis in patients with rheumatoid arthritis (RA).

Method: The patients with RA were retrospectively recruited from January 2020 to March 2022. Five radiologists with different levels of US experience were recruited for the reader study (R1-5), which included two parts.

View Article and Find Full Text PDF