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Preamble: Robotic magnetic navigation (RMN)-guided catheter ablation (CA) technology has been used for the treatment of cardiac arrhythmias for almost 20 years. Various studies reported that RMN allows for high catheter stability, improved lesion formation and a superior safety profile. So far, no guidelines or recommendations on RMN-guided CA have been published.
Purpose: The aim of this consensus paper was to summarize knowledge and provide recommendations on management of arrhythmias using RMN-guided CA as treatment of atrial fibrillation (AF) and ventricular arrhythmias (VA).
Methodology: An expert writing group, performed a detailed review of available literature, and drawing on their own experience, drafted and voted on recommendations and summarized current knowledge and practice in the field. Recommendations on RMN-guided CA are presented in a guideline format with three levels of recommendations to serve as a reference for best practices in RMN procedures. Each recommendation is accompanied by supportive text and references. The various sections cover the practical spectrum from system and patient set-up, EP laboratory staffing, combination of RMN with fluoroscopy and mapping systems, use of automation features and ablation settings and targets, for different cardiac arrhythmias.
Conclusion: This manuscript, presenting the combined experience of expert robotic users and knowledge from the available literature, offers a unique resource for providers interested in the use of RMN in the treatment of cardiac arrhythmias.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11466809 | PMC |
http://dx.doi.org/10.3389/fcvm.2024.1431396 | DOI Listing |
Heart Rhythm
September 2025
Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, United States. Electronic address:
Background: Electronic nicotine delivery systems (ENDS) utilize "E-liquids" in order to generate "E-vapor", an inhalable aerosolized mixture containing nicotine and flavors. Flavored ENDS are very popular among teens who vape, however, the possible cardiac electrophysiological harm of inhalation exposure to flavored ENDS are not fully understood.
Objective: To test if inhalation exposure to flavoring carbonyls in e-liquids compromises mitochondrial integrity, increases oxidative stress, and leads to cardiac electrophysiological toxicity.
Exp Physiol
September 2025
Unit of Cardiac Physiology, Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Sciences Centre, 3.24 Core Technology Facility, University of Manchester, Manchester, UK.
The phosphodiesterase-5 inhibitor sildenafil suppresses ventricular arrhythmias in a sheep model of drug-induced long QT. In that study, ventricular arrhythmias were abolished by reducing premature ventricular complexes (PVCs) and delaying PVC onset, thus preventing 'R-on-T' ventricular tachycardia. Evidence for effects in humans with arrhythmias is lacking.
View Article and Find Full Text PDFJ Interv Card Electrophysiol
September 2025
Cardiac Ablation Solutions, Medtronic, Minneapolis, MN, USA.
Background: Catheter ablation is beneficial in patients with symptomatic persistent atrial fibrillation (PerAF), and pulsed field ablation (PFA) is a promising energy source to safely and durably create ablation lesions. However, catheter-specific "PFA waveforms and designs" result in effectiveness and safety profiles that are not transferable to other PFA technologies. A head-to-head comparison between the dual-energy, wide-footprint lattice-tip (Sphere-9, Medtronic) and pentaspline PFA catheter (Farawave, Boston Scientific) is not yet available.
View Article and Find Full Text PDFRev Med Suisse
August 2025
Service de cardiologie, HFR Fribourg - Hôpital cantonal, 1752 Villars-sur-Glâne.
Atrial fibrillation (AF) is common in the elderly and often incidental. While anticoagulation is facilitated by risk-stratification scores, rate versus rhythm-control in the elderly and likely asymptomatic population remain challenging. We report an 80-year-old male with newly diagnosed slow AF, referred for an electrical cardioversion after amiodarone loading.
View Article and Find Full Text PDFAnn Noninvasive Electrocardiol
September 2025
Azrieli Faculty of Medicine Bar Ilan University, Safed, Israel.
Objective: To investigate two conditions that have been poorly investigated in the medical literature before in the context of atrial fibrillation: the coexistence and association of right or left bundle branch block and axis deviation in patients with permanent atrial fibrillation compared to the control group of healthy subjects with sinus rhythm.
Material And Methods: We conducted an analytic, retrospective observational study performed at Ziv Medical Center, Safed, Israel, collecting data from medical history records of all patients that have been diagnosed with permanent atrial fibrillation versus healthy controlled patients with normal sinus rhythm. We analyzed their ECGs in order to assess the presence of any bundle branch block and/or axis deviation.