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Article Abstract
Correlative light and electron microscopy (CLEM) pipelines serve to integrate the imaging modalities of fluorescence light microscopy (FLM) and cryogenic electron microscopy (cryo-EM) to produce contextually relevant high-resolution structural snapshots of biological systems. Innovations in sample preparation, instrumentation, imaging, and data processing have advanced the field of cryo-EM. This review focuses on prior work and recent developments in the field of cryo- EM that support further integration of technologies for correlative microscopy workflows.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11602379 | PMC |
| http://dx.doi.org/10.1016/j.sbi.2024.102934 | DOI Listing |
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