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Introduction: Alcoholism is a major global public health concern associated with numerous health conditions. Alcohol use has been a cultural part of several ethnic groups in Nepal. This study aimed to explore the qualitative dimension of alcohol use, its promoting factors, and consequences in Nepalese communities.
Methods: Qualitative study was conducted among 20 older adults belonging to the Magar community of Mathagadhi Rural Municipality, Lumbini Province, Nepal after acquiring ethical approval from Institutional Review Committee of CiST College (Reference number: 179/078/079). The data were analyzed using inductive thematic analysis, and themes were identified based on participants' responses to explore promoting factors for alcohol consumption along with its consequences.
Results: Traditional beliefs, cultural practices, and socioeconomic factors were the major contributors to alcohol misuse. Increased alcohol consumption during old age was perceived to be associated with body pain, tension, painful life events, and loneliness.
Conclusions: A conflicting perception was observed, where some of the participants expressed the need to promote alcohol use as a part of their culture while some shared the view that the use of alcohol as a cultural practice should be limited. This study highlights the need for culturally appropriate interventions to address alcohol misuse among indigenous communities. Interventions should focus on addressing traditional beliefs and cultural practices that normalize alcohol consumption and the social and economic problems associated with alcohol misuse.
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http://dx.doi.org/10.31729/jnma.8495 | DOI Listing |
Hepatology
September 2025
Department of Gastroenterology and Hepatology, UT Southwestern, Dallas, TX.
Background: The clinical course and outcomes of alcohol-associated hepatitis (AH) remain poorly understood. Major adverse liver outcomes (MALO) do not capture the added risk of return to drinking (RTD). We examined the natural history of AH and developed a composite endpoint using a contemporary observational cohort of AH.
View Article and Find Full Text PDFPLoS One
September 2025
Department Chemicals and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Tattoos and permanent make-up (PMU) gain increasing popularity among the general population. There are indications that pigments or their fragments may translocate within the body, however knowledge about possible systemic adverse effects related to tattoos is very limited. We investigated the prevalence of systemic chronic health effects including cardiovascular diseases, cancer and liver toxicity and their relationship with the presence and characteristics of tattoos and PMU as part of the LIFE-Adult-study, a population-based cohort study.
View Article and Find Full Text PDFNeurol Res
September 2025
Department of Neurology, The First Affiliated Hospital of Jiamusi University, Jiamusi, People's Republic of China.
Background: We conducted a transcriptomic analysis to examine cerebellar transcriptional changes in a mouse model of chronic intermittent alcohol exposure.
Methods: We established a mouse model of chronic intermittent alcohol exposure and conducted a cerebellar transcriptomic analysis. After identifying differentially expressed genes, we analyzed pathway enrichment using the Kyoto Encyclopedia of Genes and Genomes and Gene Ontology.
J Addict Nurs
September 2025
Irma Alvarado, PhD, MSN, RN, HACP, Hoang Nguyen, PhD, and Cindy West, DNP, APRN, CRNA, School of Nursing, UTMB Health, Galveston, Texas.
Introduction: Health professionals may be susceptible to misusing alcohol due to stress and burnout. This is especially true in states with high alcohol consumption. Health care organizations can implement evidence-based policies, programs, and solutions that identify, address, and help prevent adverse outcomes and burnout for health workers.
View Article and Find Full Text PDFJ Addict Nurs
September 2025
Cecilie W. Toudahl, MSc, The College of Nursing, University of South Carolina, Columbia, South Carolina.a.
Substance misuse among college students continues to rise, with polysubstance use becoming increasingly common. Alcohol remains the most prevalent substance, with heavy episodic and high-quantity drinking linked to serious consequences, including injuries, assaults, and deaths. Concurrent use of alcohol and cannabis, as well as other illicit drugs, further compounds risks to health, safety, and academic functioning.
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