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This work predicts, hot flow curves of 2205 DSS using strain-compensated Arrhenius rate-type constitutive model. Twenty-five (25) × Ø10 diameter × 15 mm height cylindrical samples were hot compressed at a temperature between 850 and 1050 °C at an interval of 50 °C and strain rates between 0.001 and 5 s, using Gleeble 1500D. After the tests, corrected flow curves were plotted followed by computation of deformations constants at various deformation conditions using steady state stress. The values of the constants were (α = 0.009708, Q = 445 kJ/mol and n = 3.7) and seemed comparable to the previous studies of DSS. Steady state predictive model was then constructed using the calculated constants and showed a reasonably good accuracy with low value of MARE = 7.78%. Furthermore, calculated strain compensated Arrhenius rate type model was used to predict flow curves at various deformation. The model had a good estimation of flow curves of flow curves at 900-1050 °C across all strain rates as reflected by MARE = 5.47%. A notable discrepancy between predicted and experimental flow stress was observed at 850 °C and across all the strain rates. A model refinement using generalised reduced gradient improved the accuracy of the model by 34.7% despite deformation conditions at 850 °C and low strain rates (0.01/ 0.1) s showing minimum improvement. Further modification of Z-parameter by compensating for the strain rate improved the accuracy of the model at 850 °C/0.01 s/0.1 s. Lastly, a comparison of the current model with the other non-linear model showed that the latter was more accurate in estimation of flow curves since it relied on characteristics flow stress points controlled by underlying active deformation mechanisms.
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http://dx.doi.org/10.1038/s41598-024-72441-9 | DOI Listing |
J Thorac Cardiovasc Surg
September 2025
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota. Electronic address:
Introduction: Goals of left ventricular assist device (LVAD) therapy includes low rates of right ventricular failure (RVF) and favorable survival outcomes. However, conventional metrics often fail to capture its physiologic complexity. We evaluated the prognostic utility of the Active Cardiac Index (ActCI) and Passive Cardiac Index (PasCI)-which reflect cardiac output driven by active RV contractility and passive venous return, respectively.
View Article and Find Full Text PDFJAMA Cardiol
September 2025
Department of Cardiology, Inselspital University Hospital of Bern, University of Bern, Bern, Switzerland.
Importance: Right anomalous aortic origin of a coronary artery (R-AAOCA) is a rare congenital condition increasingly diagnosed with the growing use of cardiac imaging. Due to dynamic compression of the anomalous vessel, invasive fractional flow reserve (FFR) during a dobutamine-atropine volume challenge (FFR-dobutamine) is considered the reference standard. A reliable alternative method is needed to reduce extensive invasive testing, but it remains uncertain whether noninvasive imaging can accurately assess the hemodynamic relevance of R-AAOCA.
View Article and Find Full Text PDFRev Cardiovasc Med
August 2025
Cardiovascular Department, Xiyuan Hospital of China Academy of Chinese Medical Sciences, 100091 Beijing, China.
Background: While the invasive index of microcirculation resistance (IMR) remains the gold standard for diagnosing coronary microvascular dysfunction (CMD), its clinical adoption is limited by procedural complexity and cost. Angiography-based IMR (Angio-IMR), a computational angiography-based method, offers a promising alternative. This study evaluates the diagnostic efficacy of Angio-IMR for CMD detection in angina pectoris (AP).
View Article and Find Full Text PDFVet World
July 2025
Laboratory of Immunochemistry and Immunobiotechnology, National Center for Biotechnology, 010000, Astana, Kazakhstan.
Background And Aim: Bovine babesiosis, caused by , poses significant economic challenges to Kazakhstan's cattle industry. Early and accurate detection is crucial for interrupting transmission cycles, particularly in regions lacking advanced diagnostic infrastructure. This study aimed to develop a rapid lateral flow immunoassay (LFIA) using a recombinant C-terminal fragment of the recombinant rhoptry-associated protein 1 (rRap1) antigen for the serodiagnosis of bovine babesiosis.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Department of Clinical Laboratory, Beijing Huilongguan Hospital, 100096 Beijing, China.
Objective: To analyze the correlation between interleukin-5 (IL-5), eosinophils (EOS), and immunoglobulin A (IgA) levels with schizophrenia, and assess their potential as auxiliary diagnostic markers for schizophrenia.
Methods: This study comprised 57 patients with first-episode schizophrenia and 340 patients with recurrent or chronic schizophrenia who were hospitalized at Beijing Huilongguan Hospital from March 2023 to August 2024, and 72 healthy volunteers were recruited as the control group. Fasting venous blood samples were collected from all participants on the second day after admission.