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Pesticides are extensively utilized in contemporary agriculture to manage pests, enhance crop yields, and sustain productivity. Nevertheless, the persistent herbicide represents a dual-edged weapon. On one hand, their prolonged efficacy enables reduced application frequency during crop growth seasons, resulting in cost savings on labor. However, the presence of these residues within fields poses safety risks to soil quality, sensitive crops in subsequent rotations, agricultural product quality, and the ecological environment. This review presents a comprehensive review on the mechanisms of action, application risks, ecotoxicology, and residue analysis methods of nine representative persistent herbicides (namely, atrazine, imazethapyr, imazapic, mesosulfuron-methyl, halosulfuron-methyl, fomesafen, diflufenican, quinclorac, and pyroxasulfone). The objective is to guide their scientific and rational utilization in agricultural practices while minimizing phytotoxicity risks and effectively monitoring and controlling soil pollution. These can not only provide practical recommendations for mitigating potential plant toxicity and ecological environmental risks but also contribute valuable technical insights for efficient soil pollution monitoring and prevention. Additionally, unaddressed research objectives were also anticipated.
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http://dx.doi.org/10.1021/acs.jafc.4c04537 | DOI Listing |
BMC Health Serv Res
September 2025
Institute of General Practice, Rostock University Medical Center, Doberaner Str. 142, Rostock, 18057, Germany.
Background: Post-viral syndromes, including long- and post-COVID, often lead to persistent symptoms such as fatigue and dyspnoea, affecting patients' daily lives and ability to work. The COVI-Care M-V trial examines whether interprofessional, patient-centred teleconsultations, initiated by general practitioners in cooperation with specialists, can help reduce symptom burden and improve care for patients.
Methods: To evaluate the effectiveness of the intervention under routine care conditions, a cluster-randomised controlled trial is being conducted.
NPJ Antimicrob Resist
September 2025
Antimicrobial Resistance & Microbiome Research Group, Department of Biology, The Kathleen Lonsdale Institute for Human Health Research, Maynooth University, Maynooth, Co, Kildare, Ireland.
Plasmids facilitate antimicrobial resistance (AMR) gene spread via horizontal gene transfer, yet the mobility of genes in wastewater treatment plant (WWTP) resistomes remains unclear. We sequenced 173 circularised plasmids transferred from WWTP effluent into Escherichia coli and characterised their genetic content. Multiple multidrug-resistant plasmids were identified, with a significant number of mega-plasmids (>100 kb).
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Twin Research and Genetic Epidemiology, King's College London, London, UK
Objectives: To estimate the association between socioeconomic background (derived from household main earner occupation when the survey respondent was aged 14 years old) and likelihood of working as a doctor in adulthood in the UK, and estimate how associations varied over time for respondents who turned 18 years old in different decades.
Design: Observational study of 10 years of pooled data from a nationally representative government survey.
Setting: The United Kingdom (UK).
JMIR Res Protoc
September 2025
Moores Cancer Center, University of California, San Diego, La Jolla, CA, United States.
Background: Cancer screening nonadherence persists among adults who are deaf, deafblind, and hard of hearing (DDBHH). These barriers span individual, clinician, and health care system levels, contributing to difficulties understanding cancer information, accessing screening services, and following treatment directives. Critical communication barriers include ineffective patient-physician communication, limited access to American Sign Language (ASL) cancer information, misconceptions about medical procedures, insurance navigation difficulties, and intersectional barriers for multiply marginalized individuals.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Centre for Research Impact & Outcome, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India; Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, 73000, Thailand. Electronic address:
Magnetic chitosan nanoparticles represent a promising platform in targeted drug delivery by merging the biocompatibility and mucoadhesiveness of chitosan with the superparamagnetic iron-oxide cores magnetite (Fe₃O₄) or maghemite (γ-Fe₂O₃). This synergy enables enhanced therapeutic precision through external magnetic guidance, controlled release, and stimuli-responsive behavior. MCNPs are particularly valuable in oncology, allowing site-specific drug delivery, magnetic hyperthermia, and real-time imaging via MRI.
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