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Background: Dispersal of gram-negative bacilli from sink drains has been implicated as a source of transmission in multiple outbreaks.
Methods: In an acute care hospital, we assessed how often patient care supplies and other frequently touched items were within 1 meter of sink drains. We tested the efficacy of a ceiling-mounted far ultraviolet-C (UV-C) light technology for decontamination of sink bowls and surfaces near sinks with and without a wall-mounted film that reflects far UV-C light.
Results: Of 190 sinks assessed, 55 (29%) had patient care supplies or other frequently touched items within 1 meter of the drain. The far UV-C technology reduced , and on steel disk carriers by ≥1.5 log colony-forming units (CFU) in 45 minutes. On inoculated real-world items, ≥1.9 log CFU reductions in were achieved on sites in line with the light source versus 0.4-1.8 log CFU reductions on shaded surfaces. The addition of the reflective surface significantly enhanced efficacy in shaded sites ( < 0.01).
Conclusions: In a hospital setting, patient care supplies and other frequently touched items were often in proximity to sinks. The far UV-C light technology could potentially be useful for sink decontamination in high-risk areas.
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http://dx.doi.org/10.1017/ice.2024.150 | DOI Listing |
Inorg Chem
September 2025
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China.
Photocatalysis has emerged as a promising strategy to address water pollution caused by heavy metals and antibiotics. Zeolites exhibit significant potential in petrochemical catalysis; however, the development of zeolite-based photocatalysts remains a critical challenge for researchers. Herein, a novel Z-scheme heterojunction was designed and fabricated on the titanium-silicon zeolite TS-1 by modifying g-CN via a simple calcination process.
View Article and Find Full Text PDFCuad Bioet
September 2025
Universidad Francisco de Vitoria. Pozuelo de Alarcón Madrid. España.
This article examines the ethical challenges posed by NBIC emerging and converging technologies (na-notechnology, biotechnology, artificial intelligence and information technologies, and cognitive sciences) from the perspective of personalist bioethics. Their biomedical and social applications are described, high-lighting the main values at stake: dignity, life, autonomy, vulnerability, and justice. Finally, guidelines are proposed, inspired by the principles of personalist bioethics: defense of human life, therapeutic totality, responsible freedom, and justice, to ensure that technological development remains at the service of the person and the common good.
View Article and Find Full Text PDFLangmuir
September 2025
School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, People's Republic of China.
The study of the self-assembly of surfactants in aqueous solutions, though a traditional field, remains fascinating and full of novelty. In this article, the anionic perfluorodecanoic acid surfactant (PFA) is separately complexed with three hydroxyalkylamines (monoethanolamine (MEA), diethylamine (DEA), and triethanolamine (TEA)) in aqueous solutions. The transformation of aggregate morphologies from spherical unilamellar to nanotubes and then to spherical bilamellar is observed at room temperature, which is confirmed by cryo-transmission electron microscopy (cryo-TEM).
View Article and Find Full Text PDFMed Oncol
September 2025
Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Neuropeptide Y (NPY) and the voltage-gated potassium channel Kv1.3 are closely associated with breast cancer progression and apoptosis regulation, respectively. NPY receptors (NPYRs), which are overexpressed in breast tumors, contribute to tumor growth, migration, and angiogenesis.
View Article and Find Full Text PDFJ Neurooncol
September 2025
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Purpose: Glioblastoma (GBM) remains one of the most aggressive primary brain tumors with poor survival outcomes and a lack of approved therapies. A promising novel approach for GBM is the application of photodynamic therapy (PDT), a localized, light-activated treatment using tumor-selective photosensitizers. This narrative review describes the mechanisms, delivery systems, photosensitizers, and available evidence regarding the potential of PDT as a novel therapeutic approach for GBM.
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