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http://dx.doi.org/10.1097/PRS.0000000000011506 | DOI Listing |
Front Radiol
August 2025
ARTORG Center for Biomedical Research, University of Bern, Bern, Switzerland.
Future AI systems may need to provide medical professionals with explanations of AI predictions and decisions. While current XAI methods match these requirements in principle, they are too inflexible and not sufficiently geared toward clinicians' needs to fulfill this role. This paper offers a conceptual roadmap for how XAI may be integrated into future medical practice.
View Article and Find Full Text PDFAm J Geriatr Psychiatry
July 2025
Department of Psychology (CMG, JMB), Science Communication Programme, University of Otago, Dunedin, New Zealand. Electronic address:
Psilocybin's efficacy as a treatment for treatment-resistant depression (TRD) has led to a wave of new legislation permitting its usage in medical settings. Older adults are affected disproportionately by TRD and may be especially good candidates for this promising treatment. However, due to the drug's past (and present) illicit status and exposure to historic antidrug messaging, older prospective patients may hold more stigmatized attitudes towards this treatment than those who are younger.
View Article and Find Full Text PDFJ Evid Based Soc Work (2019)
August 2025
School of Social Work, Institute on Trauma and Trauma-Informed Care, University at Buffalo, Buffalo, New York, USA.
Purpose: The current study examines the construct validity of Weiner et al. (2017) implementation outcome measures in a school setting, and assesses the impact of building trauma-informed organizational capacity on acceptability, appropriateness, and feasibility of adopting and implementing trauma-informed practices in schools.
Materials And Method: The validity of the implementation outcome measures were assessed using confirmatory factor analysis (CFA).
SLAS Discov
August 2025
Department of Biochemistry, School of Biological Sciences, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana. Electronic address:
Bacterial infections and antibiotic resistance remain significant threats to global health, with millions of related deaths recorded annually. Projections that antibacterial resistance-related deaths could reach alarming proportions in the coming years, along with the shortcomings of current interventions, highlight the need for new drug targets, novel antibiotics, and revised strategies and policy actions. The bacterial cytoskeleton, rod, and divisome systems (BCRDs) perform vital cellular roles and serve as a reserve of numerous potential therapeutic targets.
View Article and Find Full Text PDFBiochim Biophys Acta Rev Cancer
July 2025
Department of Oncology, The First Affiliated Hospital of Yangtze University, Jingzhou 434000, China. Electronic address:
Bone metastasis is a significant clinical problem for lung cancer patients. Current studies have reported a strong relationship between the progression of bone metastases from lung cancer and inflammatory cytokines, which can modulate the tumor microenvironment (TME) and promote the migration of tumor cells. Interleukin-6 (IL-6) family cytokines are critical components of the immune microenvironment secreted by several cell types in vivo.
View Article and Find Full Text PDF