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Purpose: To assess the effectiveness of applying digital health palliative care to improve symptoms, mood, and quality of life in patients with advanced cancer.
Methods: We searched PubMed, Embase, Web of Science, Cochrane Library (CENTRAL), and CINAHL databases on November 16, 2023, to identify randomized controlled trials of the impact of palliative care applying digital health on patients with advanced cancer. The Cochrane Risk of Bias Tool version 1.0 was used to evaluate the quality of randomized controlled trials.
Results: A total of 20 randomized controlled trials were included, of which 18 were meta-analyzed. Compared with usual care, palliative care applying digital health was effective in improving symptoms (SMD = -0.21, 95% CI: -0.37 to -0.06, P = 0.007) and reducing the intensity of pain (SMD = -0.49, 95% CI: -0.85 to -0.13, P = 0.008) in patients with advanced cancer, but no effective improvement in depressive symptoms, anxiety symptoms, or quality of life was found.
Conclusions: Our systematic review provides evidence that palliative care applying digital health has great potential to improve symptoms in patients with advanced cancer, but more research is needed to explore its impact on mood and quality of life.
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http://dx.doi.org/10.1007/s00520-024-08866-9 | DOI Listing |
Cyberpsychol Behav Soc Netw
September 2025
Humane Technology Lab, Università Cattolica del Sacro Cuore, Milan, Italy.
Med Sci Monit
August 2025
Science Editor, Medical Science Monitor, International Scientific Information, Inc., Melville, NY, USA.
Real-world data are routinely collected data associated with patient health status or delivery of health care from sources including patient registries, electronic health records (EHRs), medical claims data, or digital health technologies. Real-world evidence is generated from specified clinical real-world data and includes evidence of the use, benefits, and risks of a medical product. Analysis of real-world data is the basis of real-world evidence to support the use and potential benefits or risks of a medical product.
View Article and Find Full Text PDFCurr Alzheimer Res
September 2025
School of Biosciences, Faculty of Health and Medical Sciences, Taylor's University, 47500 Subang Jaya, Selangor, Malaysia.
Introduction: Alzheimer's disease is expressed as chronic neuroinflammation in the brain, which results in neuronal dysfunction, aberrant protein folding, and declining cognitive abilities. miR-146a-5p is a potent anti-inflammatory agent that can be used to treat several inflammatory diseases, as well as promote wound healing. Our research aimed to utilize network pharmacology to elucidate the therapeutic potential of miR-146a-5p in treating Alzheimer's disease using a biocomputational approach.
View Article and Find Full Text PDFAlzheimers Res Ther
September 2025
Motor Control and Learning Group, Institute of Human Movement Sciences and Sport, Department of Health Sciences and Technology, ETH Zurich, Leopold-Ruzicka-Weg 4, Zurich, 8093, Switzerland.
Chemosphere
September 2025
Azerbaijan National Academy of Sciences, Institute of Geography, Baku, AZ1073, Azerbaijan.
This study presents the first integrated assessment of plastic pollution at the Kura River delta, where the river enters the hydrologically enclosed Caspian Sea. We applied a modular toolbox comprising four complementary components: high-resolution hydrodynamic modeling to predict debris convergence zones, UAV-based mapping to survey shoreline conditions, automated object-based image analysis for debris detection and classification, and standardized field monitoring by trained community participants for ground-truthing and source identification. Using this framework, we identified debris accumulation hotspots and developed a replicable approach for assessing plastic pollution in semi-enclosed systems.
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