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To address the issue of harsh marine background noise impacting the monitoring signal of fiber-optic hydrophones, we propose a low-noise fiber Bragg grating (FBG) hydroacoustic monitoring system with a reference sensor based on genetic algorithm backpropagation (GA-BP). Through theoretical analysis, we deduce the noise suppression steps of the GA-BP algorithm based on the reference sensor and construct train and test sets based on the data from the reference sensor and monitoring sensor at different times, optimizing the GA-BP algorithm to find the best fitting results and thereby obtaining the low-noise monitoring signal. Experimental results from the anechoic tank show that the proposed method can suppress background noise interference on effective signals and that the suppression effect improves as the background noise increases. The sound pressure sensitivity ranges from -173.76 dB to -171.33 dB at frequencies of 8 kHz to 12 kHz, with a response flatness of less than 2.43 dB. The noise suppression effect is obvious under the condition of poor signal-to-noise ratio (SNR), which can reach more than 18.3 dB. The advantages of the proposed algorithm in array signal processing are further demonstrated by the directivity experiment, which proves that the algorithm has a great potential for engineering applications in harsh marine environment.
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http://dx.doi.org/10.3390/s24175733 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
Agonist-induced interaction of G protein-coupled receptors (GPCRs) with β-arrestins (βarrs) is a critical mechanism that regulates the spatiotemporal pattern of receptor localization and signaling. While the underlying mechanism governing GPCR-βarr interaction is primarily conserved and involves receptor activation and phosphorylation, there are several examples of receptor-specific fine-tuning of βarr-mediated functional outcomes. Considering the key contribution of conformational plasticity of βarrs in driving receptor-specific functional responses, it is important to develop novel sensors capable of reporting distinct βarr conformations in cellular context.
View Article and Find Full Text PDFJ Pain
September 2025
Cyber-physical Health and Assistive Robotics Technologies Research Group, University of Nottingham, United Kingdom; School of Computer Science, University of Nottingham, Nottingham, United Kingdom.
Neck pain is among the most prevalent musculoskeletal conditions worldwide. The underlying cause mostly remains unidentified, classified as non-specific neck pain. Pain can alter movement patterns and physiological responses, suggesting that certain biomechanical and physiological changes may serve as objective biomarkers for non-specific neck pain.
View Article and Find Full Text PDFJ Fluoresc
September 2025
School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, 541004, China.
The pervasive concern regarding veterinary drug residues in food necessitates advanced detection solutions, particularly addressing limitations of conventional methods reliant on large-scale instrumentation that incur prolonged analysis duration, complex sample preparation, and lack of real-time on-site capability. A portable "single response-on" molecularly imprinted ratiometric fluorescent paper-based sensor was developed for quantifying fleroxacin (FLX) residues in animal-derived foods, wherein B, N-co-doped MXene quantum dot (B, N-MQD) was synthesized and combined with BCP-Eu as dual-emission fluorophores, while FLX- molecularly imprinted polymer (FLX-MIP) was engineered using functionalized Nano-SiO as the carrier. Concentration-dependent fluorescence enhancement at 574 nm was exhibited with invariant reference signal at 411 nm, achieving a 36-fold lower detection limit (0.
View Article and Find Full Text PDFRev Sci Instrum
September 2025
State Key Laboratory of Deep Earth Exploration and Imaging, Jilin University, Changchun 130026, People's Republic of China.
In the semi-airborne frequency-domain electromagnetic (SAFEM) method, the total magnetic intensity (TMI) is derived from the vector synthesis of triaxial inductive magnetic sensors. However, non-orthogonal errors in the sensors introduce measurement inaccuracies. Traditional calibration techniques are unsuitable for induction magnetic sensors because they require either static magnetic field measurements or complex alternating current reference fields.
View Article and Find Full Text PDFBMJ Open Sport Exerc Med
September 2025
Servizio di Endocrinologia e Diabetologia, Repubblica e Cantone Ticino Ente Ospedaliero Cantonale, Bellinzona, TI, Switzerland.
Background: The use of continuous glucose monitors (CGM) in scuba diving for patients with type 1 diabetes (T1DM) shows potential but faces challenges related to accuracy. Previous research has highlighted the poor accuracy of the Dexcom G7 (DG7) in repetitive diving contexts. This study investigates the impact of calibration on the accuracy of DG7, providing valuable insights for patients and clinicians.
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