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Introduction: Cardiopulmonary resuscitation (CPR) in microgravity requires specific methods to counteract weightlessness. Automatic chest compression devices (ACCDs) could improve CPR in microgravity. We aimed to compare ACCDs versus manual CPR in microgravity simulated through parabolic flights.
Methods: This prospective, open, controlled study compared 3 ACCDs (LUCAS 3©, AUTOPULSE©, EASYPULSE©) to manual CPR during the 66th CNES (Centre National d'Etudes Spatiales) parabolic flights campaign onboard the Novespace Air Zero-G A310 aircraft. Chest compression depths and rates were monitored by a Laerdal© Resusci-Ann-QCPR manikin.
Results: The LUCAS 3© device had a median compression depth of 53.0 [53.0-54.0] mm, significantly higher than the EASYPULSE©, AUTOPULSE©, and Manual CPR (Handstand method), measured at 29.0 [26.0-32.0] mm, 29.0 [27.5-30.7] mm and 34.5 [29.6-43.3] mm, respectively (p value < 0.001). Compression rates were 101 [101-101], 100 [100-100] and 80 [80-80] compressions per minute (cpm) for the LUCAS 3©, EASYPULSE©, and AUTOPULSE©, respectively. Manual CPR provided a significantly higher compression rate with 115 [109-123] cpm (p value < 0.001).
Conclusion: Only LUCAS 3© provided effective CPR according to international guidelines. ACCDs should implement microgravity CPR algorithms.
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http://dx.doi.org/10.1016/j.resuscitation.2024.110385 | DOI Listing |
Resusc Plus
November 2025
Helicopter Emergency Medical Service Lifeliner 3, Nijmegen, the Netherlands.
Background: Out-of-hospital cardiac arrest management prioritises effective treatment, with high-quality chest compressions and timely defibrillation being essential. While current European Resuscitation Council guidelines recommend sternal-apical defibrillator pad placement, alternative positions such as anterior-posterior (AP) are gaining interest. The integration of secondary AP pad placement with mechanical cardiopulmonary resuscitation devices (mCPR) remains underexplored.
View Article and Find Full Text PDFJ Acute Med
September 2025
Rush University Medical Center Department of Emergency Medicine Chicago, IL USA.
Cardiac arrest is a common condition with low survival rates. Point-of-care ultrasound (POCUS) has been increasingly integrated in cardiac arrest care to enhance diagnostic accuracy and guide interventions. POCUS can be divided into cardiac and non-cardiac applications.
View Article and Find Full Text PDFCureus
August 2025
Allergy and Immunology, Wilford Hall Medical Center, San Antonio, USA.
We present two patients who presented with symptoms that overlap with asthma, but upon further diagnostic evaluation, were revealed to have underlying malignancy. These cases highlight the importance of objective evidence-based evaluation in unveiling diagnoses previously mislabeled as asthma. The first patient was a 51-year-old with one year of cough and waning albuterol responsiveness, with worsening orthopnea and exertional dyspnea.
View Article and Find Full Text PDFCureus
August 2025
Department of Obstetrics and Gynecology, University of Ioannina, Ioannina, GRC.
A 34-year-old nulligravida with schizophrenia presented after four months of progressive abdominal distension, culminating in severe respiratory compromise. An urgent transabdominal ultrasound was initially interpreted as massive ascites; however, its diagnostic accuracy was limited by the extreme abdominal distension and the patient's inability to change position due to respiratory distress. Further evaluation with CT of the thorax and abdomen revealed a 35 × 42 × 48.
View Article and Find Full Text PDFPain Res Manag
September 2025
Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Pectus excavatum is a common congenital chest wall deformity that can lead to significant cardiopulmonary compression and psychological distress. The minimally invasive Nuss procedure is the standard treatment, but it often results in severe postoperative pain. Effective perioperative pain management is essential to enhance recovery and improve patient outcomes.
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