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http://dx.doi.org/10.2174/0115734056323644240817114945 | DOI Listing |
Technol Cancer Res Treat
September 2025
Department of Nephrology, Dongyang People's Hospital, Dongyang, China.
ObjectiveTo evaluate the diagnostic performance of a combined model incorporating ultrasound video-based radiomics features and clinical variables for distinguishing between benign and malignant breast lesions.MethodsA total of 346 patients (173 benign and 173 malignant) were retrospectively enrolled. Breast ultrasound videos were acquired and processed using semi-automatic segmentation in 3D Slicer.
View Article and Find Full Text PDFCureus
August 2025
Department of Radiology, Aichi Medical University, Nagakute, JPN.
Background This study was conducted to examine the effects of moving the isocenter (IC) position from the lesion to the center of the brain on stereotactic radiosurgery (SRS) planning with volumetric-modulated arcs (VMA) using the High-Definition Dynamic Radiosurgery (HDRS) platform, a combination of the Agility multileaf collimator (MLC) (Elekta AB, Stockholm, Sweden) and the Monaco planning system (Elekta AB), for single brain metastases (BMs). Methodology The study subject included 36 clinical BMs with the gross tumor volume (GTV) ranging from 0.04 to 48.
View Article and Find Full Text PDFBioact Mater
December 2025
Department of Plastic Surgery, Peking University Third Hospital, Beijing, 100191, China.
Craniofacial muscles are essential for a variety of functions, including fine facial expressions. Severe injuries to these muscles often lead to more devastating consequences than limb muscle injuries, resulting in the loss of critical functions such as mastication and eyelid closure, as well as facial aesthetic impairment. Therefore, the development of targeted repair strategies for craniofacial muscle injuries is crucial.
View Article and Find Full Text PDFFront Neurol
August 2025
Department of Neuroradiology, Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France.
Objective: This study evaluates age- and sex-related differences in brain volume, including normalized gray matter (nGM), normalized white matter (nWM), cerebrospinal fluid (CSF) volume, and total intracranial volume (TIV) in cognitively normal adults using automatic volume segmentation on 3.0 Tesla MRI.
Methods: A prospective cross-sectional study conducted from October 2021 to September 2022 included 110 cognitively normal participants.
Bone Rep
September 2025
Department of Orthopaedic Surgery, Vanderbilt University Medical Center, 1215 21st Ave. S., Suite 4200, Nashville, TN 37232, USA.
This study applied Raman spectroscopy (RS) to ex vivo human cadaveric femoral mid-diaphysis cortical bone specimens ( = 118 donors; age range 21-101 years) to predict fracture toughness properties via machine learning (ML) models. Spectral features, together with demographic variables (age, sex) and structural parameters (cortical porosity, volumetric bone mineral density), were fed into support vector regression (SVR), extreme tree regression (ETR), extreme gradient boosting (XGB), and ensemble models to predict fracture-toughness metrics such as crack-initiation toughness (K) and energy-to-fracture (J-integral). Feature selection was based on Raman-derived mineral and organic matrix parameters, such as νPhosphate (PO)/CH-wag, νPO/Amide I, and others, to capture the complex composition of bone.
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