Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Approximately 25% of the general population has a patent foramen ovale (PFO) that remains asymptomatic in the vast majority. Right-to-left shunt (RLS)-mediated hypoxaemia is a rare associated condition of PFO.
Case Summary: This report describes a case of percutaneous PFO closure for hypoxaemia in a 73-year-old patient showing immediate clinical benefit. She experienced progressive dyspnoea on exertion requiring oxygen therapy. SaO2 was 87% at rest without oxygen therapy, which increased to 98% after percutaneous PFO closure.
Discussion: Most PFOs remain clinically insignificant but RLS-mediated hypoxaemia is a rare phenomenon that can occur even at advanced age. Percutaneous PFO closure is a safe and effective therapy option that provides immediate improvement of hypoxaemia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358635 | PMC |
| http://dx.doi.org/10.1093/ehjcr/ytae415 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Transcatheter atrial septal defects and patent foramen ovale closure: Medicare utilization and reimbursements.
World J Methodol
December 2025
Department of Cardiology, University of Miami-Miller School of Medicine, Miami, FL 33136, United States.
Background: The Food and Drug Administration has approved percutaneous atrial septal defect (ASD) and patent foramen ovale (PFO) closure devices for hemodynamically significant interatrial shunts, paradoxical emboli including stroke, and decompression sickness. We aimed to study the trends in utilization and reimbursements of transcatheter ASD/PFO closure devices.
Aim: To analyze trends in utilization and Medicare reimbursements for transcatheter ASD/PFO closure procedures from 2013 to 2022.
Concomitant carcinoid heart disease and patent foramen ovale: a case report and review of literature.
Cardiooncology
September 2025
Hospital Distrital de Santarém, Santarém, Portugal.
Background: Carcinoid Heart Disease (CHD) primarily affects the right heart valves, while left heart involvement is rare and often associated with a patent foramen ovale (PFO). Early identification of a PFO in CHD can be critical to patient outcomes. A 61-year-old woman with metastatic neuroendocrine tumor presented with worsening breathlessness and hypoxemia.
View Article and Find Full Text PDFPatent Foramen Ovale (PFO) Closure in Thrombophilia as Primary Prevention in Patients Without Prior PFO-Associated Thromboembolic Events.
Cureus
July 2025
Pediatric Cardiology, Mitera Children's Hospital, Athens, GRC.
Patent foramen ovale (PFO) is a common anatomical variant with potential clinical implications in embolic phenomena. In some situations, transcatheter closure is considered a treatment option. For patients with thrombophilia who have not had embolic events, it is not always clear whether this approach is appropriate.
View Article and Find Full Text PDFPrevalence, classification, and treatment of residual shunt after patent foramen ovale closure.
EuroIntervention
August 2025
1. Pediatric Cardiology and GUCH Unit, Heart Hospital "G. Pasquinucci", National Research Council-Tuscany Foundation "G. Monasterio", Massa, Italy.
Background: Residual shunt (RS) after transcatheter patent foramen ovale (PFO) closure has been associated with an increased risk of recurrent stroke over long-term follow-up. However, RS prevalence, anatomical characteristics, and treatment strategies are poorly understood.
Aims: This study aimed to assess the prevalence and causes of RS, as well as to evaluate the safety and feasibility of its percutaneous treatment.
Alien Hand Syndrome as the Initial Presentation of Patent Foramen Ovale-Associated Stroke.
Clin Med Insights Case Rep
August 2025
Department of Internal Medicine, Hospital Universitario Fundación Santa Fe de Bogotá, Colombia.
Alien Hand Syndrome (AHS) is a rare neurological condition characterized by involuntary, goal-directed movements of a limb without conscious control. It is most often associated with stroke in specific brain regions, including the medial frontal and parietal cortices. We report the case of a 33-year-old male with no previous medical history who presented with involuntary movements of the left upper limb, describing it as "moving on its own.
View Article and Find Full Text PDF