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Background And Objective: Medicine image classification are important methods of traditional medical image analysis, but the trainable data in medical image classification is highly imbalanced and the accuracy of medical image classification models is low. In view of the above two common problems in medical image classification. This study aims to: (i) effectively solve the problem of poor training effect caused by the imbalance of class imbalanced data sets. (ii) propose a network framework suitable for improving medical image classification results, which needs to be superior to existing methods.
Methods: In this paper, we put in the diffusion model multi-scale feature fusion network (DMSFF), which mainly uses the diffusion generation model to overcome imbalanced classes (DMOIC) on highly imbalanced medical image datasets. At the same time, it is processed according to the cropped image augmentation strategy through cropping (IASTC). Based on this, we use the new dataset to design a multi-scale feature fusion network (MSFF) that can fully utilize multiple hierarchical features. The DMSFF network can effectively solve the problems of small and imbalanced samples and low accuracy in medical image classification.
Results: We evaluated the performance of the DMSFF network on highly imbalanced medical image classification datasets APTOS2019 and ISIC2018. Compared with other classification models, our proposed DMSFF network achieved significant improvements in classification accuracy and F1 score on two datasets, reaching 0.872, 0.731, and 0.906, 0.836, respectively.
Conclusions: Our newly proposed DMSFF architecture outperforms existing methods on two datasets, and verifies the effectiveness of generative model inverse balance for imbalance class datasets and feature enhancement by multi-scale feature fusion. Further, the method can be applied to other class imbalanced data sets where the results will be improved.
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http://dx.doi.org/10.1016/j.cmpb.2024.108384 | DOI Listing |
Haematologica
September 2025
Division of Hematopathology, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine/NewYork-Presbyterian Hospital, New York, NY; Multiparametric In Situ Imaging (MISI) Laboratory, Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York.
Not available.
View Article and Find Full Text PDFClin Pediatr (Phila)
September 2025
Department of Medicine (Infectious Disease), University of Connecticut Health Center, Boston University Medical Center, Falmouth Hospital, Falmouth, MA, USA.
A total of 101 patients with a clinical picture of persisting Lyme disease seen at the University of Connecticut Health Center and Boston Medical Center were recruited for the study to determine whether persistent infection is the likely cause. Brain SPECT imaging and responses to antibiotic treatments were recorded. Patients had more than 5 symptoms lasting more than 6 months.
View Article and Find Full Text PDFStroke
September 2025
Department of Neurology, Yale School of Medicine, New Haven, CT (L.H.S.).
Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials.
View Article and Find Full Text PDFCirc Arrhythm Electrophysiol
September 2025
Department of Congenital Heart Disease, Evelina London Children's Hospital, United Kingdom (S. Chivers, T.V., V.Z., S.M., G.M., W.R., E.R., D.F.A.L., T.G.D., O.I.M., G.K.S., J.M.S.).
Background: Fetal tachycardias can cause adverse fetal outcomes including ventricular dysfunction, hydrops, and fetal demise. Postnatally, ECG is the gold standard, but, in fetal practice, echocardiography is used most frequently to diagnose and monitor fetal arrhythmias. Noninvasive extraction of the fetal ECG (fECG) may provide additional information about the electrophysiological mechanism and monitoring of intermittent arrhythmias.
View Article and Find Full Text PDFBr J Psychiatry
September 2025
Neuroscience Research Australia, Randwick, New South Wales, Australia.
Background: Individuals with a family history of bipolar disorder are at increased risk of developing affective psychopathology. Longitudinal imaging studies in young people with familial risk have been limited, and cortical developmental trajectories in the progression towards illness remain obscure.
Aims: To establish high-resolution longitudinal differences in cortical structure that are associated with risk of bipolar disorder.