Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Bilateral orbital metastases are extremely rare, and no previous literature has reported bilateral multiple orbital metastases treated with stereotactic radiosurgery (SRS). We present the impressive images of a patient with history of metastatic leiomyosarcoma with newly diagnosed bilateral multiple orbital metastases. The pre-SRS magnetic resonance imaging (MRI) showed 1 right and 2 left orbital metastatic lesions. The patient underwent SRS, and the post-SRS MRI at 2 months showed a decrease in size of the treated lesions. The positron emission tomography scan at 5 months after the treatment showed no avid F-fluorodeoxyglucose uptakes in the 3 orbital metastases. The presenting symptoms were all improved after the treatment with no adverse effects from the SRS. Our interesting images show the presence of multiple lesions in the orbital spaces with excellent treatment response post SRS. This is the first report of a patient who has bilateral and multiple orbital metastases that were successfully treated with standalone SRS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.wneu.2024.08.075 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Two-Step Semi-Automated Classification of Choroidal Metastases on MRI: Orbit Localization via Bounding Boxes Followed by Binary Classification via Evolutionary Strategies.
AJNR Am J Neuroradiol
September 2025
From the Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America (J.S.S., B.M., S.H., A.H., J.S.), and Department of Aerospace Engineering, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India (H.S.).
Background And Purpose: The choroid of the eye is a rare site for metastatic tumor spread, and as small lesions on the periphery of brain MRI studies, these choroidal metastases are often missed. To improve their detection, we aimed to use artificial intelligence to distinguish between brain MRI scans containing normal orbits and choroidal metastases.
Materials And Methods: We present a novel hierarchical deep learning framework for sequential cropping and classification on brain MRI images to detect choroidal metastases.
Radiation Therapy for Solitary Fibrous Tumor of the Orbit.
Ophthalmic Plast Reconstr Surg
September 2025
Orbital Oncology and Ophthalmic Plastic Surgery, Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center.
Solitary fibrous tumor, formerly also referred to as hemangiopericytoma, is a fibroblastic mesenchymal neoplasm of the orbit that rarely metastasizes but has a propensity for local recurrence. We describe 5 cases of orbital solitary fibrous tumors that were treated with radiation. In 3 patients, radiation therapy was given in the neoadjuvant setting prior to surgery.
View Article and Find Full Text PDFCemiplimab in advanced periocular conjunctival and cutaneous squamous cell carcinoma: a United Kingdom case series.
Orbit
September 2025
Adnexal, Moorfields Eye Hospital, London, UK.
Purpose: To evaluate the real-world efficacy, safety, and outcomes of cemiplimab for advanced periocular conjunctival and cutaneous squamous cell carcinoma (SCC).
Methods: Retrospective case series of adults treated with cemiplimab for periocular conjunctival or cutaneous SCC at Moorfields Eye Hospital (2021-2025).
Results: We included 9 patients (mean age 66, range 43-79; 56% female; 78% Caucasian).
Stereotactic Ablative Radiotherapy for Delayed Retrobulbar Metastasis of Renal Cell Carcinoma: Therapeutic Outcomes and Practical Insights.
Life (Basel)
July 2025
Department of Radiation Oncology, Keimyung University School of Medicine, Daegu 42601, Republic of Korea.
We present a rare case of delayed retrobulbar and adrenal metastases from renal cell carcinoma (RCC), diagnosed 5.5 years after radical nephrectomy. The patient exhibited symptomatic orbital involvement, with imaging revealing a hypervascular retrobulbar mass and an incidental right adrenal lesion, indicative of an oligometastatic state.
View Article and Find Full Text PDFPrimary Orbital Mucinous Adenocarcinoma: A Malignancy With Rapid Metastasis.
Cureus
July 2025
Pathology and Laboratory Medicine, Hospital Clínico Universitario, Valladolid, ESP.
Primary mucinous adenocarcinoma of the orbit is an exceptionally rare epithelial malignancy that closely mimics metastatic disease both clinically and radiologically, often delaying definitive diagnosis. We report the case of a 69-year-old man who presented with progressive ocular pain, axial proptosis, and a well-circumscribed orbital mass on imaging. Histopathological evaluation following incisional biopsy revealed a mucinous adenocarcinoma with signet ring morphology.
View Article and Find Full Text PDF