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Background: The aim of this extended review of multicenter case series is to describe the prenatal ultrasound features and pathogenetic mechanisms underlying placental and umbilical cord anomalies and their relationship with adverse perinatal outcome. From an educational point of view, the case series has been divided in three parts; Part 1 is dedicated to placental abnormalities.
Methods: Multicenter case series of women undergoing routine and extended prenatal ultrasound and perinatal obstetric care.
Results: Prenatal ultrasound findings, perinatal care, and pathology documentation in cases of placental pathology are presented.
Conclusions: Our case series review and that of the medical literature confirms the ethiopathogenetic role and involvement of placenta abnormalities in a wide variety of obstetrics diseases that may jeopardize the fetal well-being. Some of these specific pathologies are strongly associated with a high risk of poor perinatal outcome.
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http://dx.doi.org/10.1002/jcu.23773 | DOI Listing |
Nutr Clin Pract
September 2025
Department of Pediatrics, Mayo Clinic, Rochester, Minnesota, USA.
Home parenteral nutrition (HPN) is a life-sustaining therapy traditionally used as a bridge to enteral autonomy or intestinal transplantation. Increasingly, it is used for intractable feeding intolerance (IFI), which can occur near the end of life (EOL) in children with severe neurological impairment (SNI). In these cases, HPN use differs from its historical role and requires tailored outpatient planning.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Department of Otolaryngology - Head and Neck Surgery, King Fahad Specialist Hospital, Dammam, Saudi Arabia.
BACKGROUND Pediatric sinonasal tumors are rare, accounting for about 4% of all pediatric head and neck neoplasms. Due to their nonspecific symptoms such as nasal obstruction, epistaxis, and facial pain, these tumors often present diagnostic challenges and lead to delays in managment. Early and accurate diagnosis is crucial to optimize clinical outcomes.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Objective: To examine the safety and effectiveness of non-inverted ILM Free Flap combined with the SPOT technique (Sub-Perfluorocarbon liquid (PFCL) injection of Ocular viscoelastic device (OVD) Technique) in the treatment of unclosed macular holes (MHs).
Design: Retrospective interventional case series.
Participants: Eight patients (8 eyes) with persistent unclosed MHs were treated at a tertiary eye hospital in China from September 2023 to February 2025.
World Neurosurg
September 2025
Department of Orthopedics, Xinqiao Hospital, Army Military Medical University, Chongqing 400037, China. Electronic address:
Objective: The purpose of this study is to present five new cases of congenital absence of posterior elements of the axis (C2), totaling 17 cases report in the literature, and to propose an anatomical classification system for this rare condition for standardizing its management.
Methods: A retrospective review of five patients diagnosed and surgically treated for the absence of C2 posterior elements was conducted from 2017 to 2024. Clinical characteristics were summarized, and imaging studies, including X-rays, CT, and MRI were performed to define abnormalities and cord compression.