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http://dx.doi.org/10.1016/j.jaad.2024.07.1495 | DOI Listing |
World J Urol
September 2025
Department of Pharmacology, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
Purpose: To evaluate the impact of MRP inhibition by MK571 on prostate hypercontractility in diet-induced obesity, based on the hypothesis that this intervention enhances intracellular cAMP and cGMP signaling.
Methods: Adult C57BL/6 mice were divided into three groups: (i) lean, (ii) obese, and (iii) obese + MK571 (5 mg/kg/day, 14 days). The prostate was isolated for immunohistochemistry, biochemistry and functional assays.
Plant Biol (Stuttg)
September 2025
Department of Botany and Center for Biotechnology, Plant Physiology Laboratory, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Erythrina velutina is a tree that thrives in the shallow rocky soils of the dry and hot Caatinga, a unique Brazilian biome. It is rich in specialized metabolites with medicinal properties. Indeed, alkaloids and flavonoids are phytochemical markers of the genus.
View Article and Find Full Text PDFInt J Gynaecol Obstet
September 2025
WHO Collaborating Centre for Maternal and Child Health, Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
Objective: Despite advancements in maternity quality care worldwide, mistreatment of women during childbirth persists. Currently, there is a gap of knowledge on the occurrence of disrespect and abuse during childbirth in the World Health Organization (WHO) European region.
Methods: Within the IMAgiNE EURO (Improving Maternal Newborn Care in the WHO European Region During COVID-19 Pandemic) study, women 18 years and older who gave birth in healthcare facilities in the WHO European region, were invited to complete an online validated questionnaire regarding quality of maternity care.
Mar Life Sci Technol
August 2025
Laboratory of Marine Organism Taxonomy and Phylogeny, Qingdao Key Laboratory of Marine Biodiversity and Conservation, and The Key Laboratory of Experimental Marine Biology, Centre for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266000 China.
Unlabelled: The distribution of (Euphrasen, 1788) spans a pronounced latitudinal-environmental gradient from the subtropical to the subpolar zones. The species is reported to have multiple stocks along coastal China, exhibiting different spawning behaviors and habitat preferences. Such ecological variations might imply potential genetic divergence and local adaptation.
View Article and Find Full Text PDFCureus
August 2025
Neurosurgery, Fluminense Federal University, Niterói, BRA.
Motor neuron disease and parkinsonism syndromes associated with chronic HIV infection are extremely rare, with only a few cases reported in major medical databases. We report a case from Brazil involving a patient with a chronic, well-controlled HIV infection for approximately 15 years, demonstrating a good response to highly active antiretroviral therapy. Despite the absence of viral replication, the patient developed atypical clinical and topographical features consistent with both pyramidal and extrapyramidal syndromes.
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