98%
921
2 minutes
20
Median arcuate ligament syndrome (MALS) is a rare gastroenterological illness that arises from the compression of the celiac trunk by the fibrous arch known as the median arcuate ligament, which connects the muscular tendon of the diaphragm to the vertebral column. It is hypothesized that this syndrome arises due to the inadequate caudal migration of the celiac trunk during embryogenesis, although the exact pathophysiology behind this disease process remains unclear. While MALS is classically associated with a triad of post-prandial pain, weight loss, and epigastric bruit, the triad is often incomplete due to variations in vascular structures with collateral circulation from adjacent vessels. When symptoms are present, they can be vague and often characterized as unexplained nausea, vomiting, diarrhea, or flatulence. Frequently, MALS is identified incidentally upon imaging of the abdomen in response to these nonspecific complaints. We present the case of a patient suffering from MALS in which a rare anatomic variant of the celiac trunk was identified.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322695 | PMC |
http://dx.doi.org/10.7759/cureus.64514 | DOI Listing |
J Vasc Surg Cases Innov Tech
December 2025
Department of Cardiovascular Surgery, Ogaki Municipal Hospital, Ogaki, Japan.
Pancreaticoduodenal artery (PDA) aneurysm is rare. A 79-year-old man with an abdominal aortic aneurysm and celiac artery stenosis caused by median arcuate ligament compression underwent endovascular aneurysm repair. On postoperative day 1, the patient experienced sudden abdominal pain and hypotension.
View Article and Find Full Text PDFCurr Opin Pediatr
October 2025
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Stanford University School of Medicine and Stanford Children's Health, Palo Alto, California, USA.
Purpose Of Review: Median arcuate ligament syndrome (MALS) is understood to be a condition where compression of the celiac artery by the median arcuate ligament (MAL) may lead to symptoms of postprandial or exercise-induced abdominal pain, nausea, vomiting, diarrhea, oral aversion, and weight loss. This review summarizes recent literature on pediatric MALS while highlighting the challenges, comorbidities, and controversies encountered in this condition.
Recent Findings: The pathophysiologic mechanism by which MALS leads to pain is currently unknown.
Kidney Med
September 2025
UCLA Health, Department of Pathology and Laboratory Medicine, Los Angeles, CA.
Rationale & Objective: Pathological connection between the kidney tubules and veins is known as a microscopic tubulovenous communication we refer to as a tubulovenous fistula (TVF). This finding has been reported in a few small case reports, but no systematic examination of cases across various clinical settings detailing their histologic spectrum and associated clinical/pathologic findings has been performed.
Study Design: Case series and literature review.
World J Clin Cases
September 2025
Department of General Internal Medicine 2, Kawasaki Medical School, Okayama 7008505, Japan.
Background: A 56-year-old female presented with acute abdominal pain due to a ruptured pseudoaneurysm associated with median arcuate ligament syndrome (MALS), a rare condition caused by the compression of the celiac artery by the median arcuate ligament (MAL), potentially leading to ischemia, aneurysm formation, and rupture.
Case Summary: Computed tomography revealed a retroperitoneal hematoma, celiac artery stenosis, and two aneurysms in the inferior pancreaticoduodenal artery. Hemostasis was achieved using transcatheter arterial embolization.
J Vasc Surg
August 2025
Aortic Center, Department of Vascular Surgery, Hôpital Marie Lannelongue, Groupe hospitalier Paris Saint Joseph, INSERM UMR_S 999, Université Paris-Saclay, Paris, France. Electronic address:
Objective: To evaluate the impact of a new dedicated stepped balloon mounted bridging stent (BS) on procedural time, radiation exposure, and early technical outcomes in patients undergoing Fenestrated Endovascular Aortic Repair (FEVAR).
Methods: A retrospective study was conducted on patients treated with four-fenestration FEVAR at a high-volume aortic center between March 2020 and March 2025. Patients were categorized into three groups: Standard balloon BS (Begraft, BG, Bentley) and renal access with preloaded renal catheters; Standard balloon BS (BG) and renal access with steerable sheaths; and stepped balloon BS (BeFlared, BF, Bentley) and renal access with steerable sheaths.