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Objectives: To develop a deep learning (DL)-model using convolutional neural networks (CNN) to automatically identify the fetal head position at transperineal ultrasound in the second stage of labor.
Material And Methods: Prospective, multicenter study including singleton, term, cephalic pregnancies in the second stage of labor. We assessed the fetal head position using transabdominal ultrasound and subsequently, obtained an image of the fetal head on the axial plane using transperineal ultrasound and labeled it according to the transabdominal ultrasound findings. The ultrasound images were randomly allocated into the three datasets containing a similar proportion of images of each subtype of fetal head position (occiput anterior, posterior, right and left transverse): the training dataset included 70 %, the validation dataset 15 %, and the testing dataset 15 % of the acquired images. The pre-trained ResNet18 model was employed as a foundational framework for feature extraction and classification. CNN was trained to differentiate between occiput anterior (OA) and non-OA positions, CNN classified fetal head malpositions into occiput posterior (OP) or occiput transverse (OT) position, and CNN classified the remaining images as right or left OT. The DL-model was constructed using three convolutional neural networks (CNN) working simultaneously for the classification of fetal head positions. The performance of the algorithm was evaluated in terms of accuracy, sensitivity, specificity, F1-score and Cohen's kappa.
Results: Between February 2018 and May 2023, 2154 transperineal images were included from eligible participants across 16 collaborating centers. The overall performance of the model for the classification of the fetal head position in the axial plane at transperineal ultrasound was excellent, with an of 94.5 % (95 % CI 92.0--97.0), a sensitivity of 95.6 % (95 % CI 96.8-100.0), a specificity of 91.2 % (95 % CI 87.3-95.1), a F1-score of 0.92 and a Cohen's kappa of 0.90. The best performance was achieved by the CNN - OA position vs fetal head malpositions - with an accuracy of 98.3 % (95 % CI 96.9-99.7), followed by CNN - OP vs OT positions - with an accuracy of 93.9 % (95 % CI 89.6-98.2), and finally, CNN - right vs left OT position - with an accuracy of 91.3 % (95 % CI 83.5-99.1).
Conclusions: We have developed a DL-model capable of assessing fetal head position using transperineal ultrasound during the second stage of labor with an excellent overall accuracy. Future studies should validate our DL model using larger datasets and real-time patients before introducing it into routine clinical practice.
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http://dx.doi.org/10.1016/j.ejogrb.2024.08.012 | DOI Listing |
Resuscitation
September 2025
Department of Pediatrics, Division of Neonatology, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Division of Neonatology, 2(nd) Floor, Main Building, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
Aim: Flow disruptions (FDs) are deviations in the progression of care that compromise safety and efficiency of a specific process. Neonatal intubation is a life-saving high-risk procedure required for delivery room (DR) management of neonates with moderate to severe congenital diaphragmatic hernia (CDH). This study evaluated FDs during DR intubation of neonates with CDH and their association with process and outcome measures.
View Article and Find Full Text PDFHum Genet
September 2025
Prenatal Diagnostic Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510620, Guangdong, China.
This study aims to assess the genetic burden of fetal congenital diaphragmatic hernia (CDH) and identify prenatal, perinatal, and postnatal predictors to improve early diagnosis, monitoring, and intervention. This study included 130 CDH fetuses who underwent invasive prenatal diagnosis, with fetal prognosis evaluated using imaging parameters such as observed-to-expected lung-to-head ratio (o/e LHR), observed-to-expected total lung volume (o/e TLV), and percent predicted lung volume (PPLV). Clinical outcomes included neonatal outcomes, extracorporeal membrane oxygenation (ECMO) requirement, and post-neonatal prognosis.
View Article and Find Full Text PDFMethodsX
December 2025
Symbiosis Institute of Technology, Pune Campus, Symbiosis International (Deemed University), Pune, India.
Accurate classification of fetal ultrasound images is critical for early diagnosis, yet remains challenging due to limited labeled data and high inter-class variability. This study presents a robust deep learning framework that combines a MobileNet backbone with multi-head self-attention and LSTM layers to enhance feature learning and temporal context. To address data scarcity and imbalance, unsupervised clustering was employed using Principal Component Analysis (PCA) for dimensionality reduction and K-means (k=4) for pseudo-label generation.
View Article and Find Full Text PDFAm J Case Rep
September 2025
Division of Pediatric Surgery, Department of Surgery, Children's Hospital Colorado, Aurora, CO, USA.
BACKGROUND Ex-utero intrapartum treatment (EXIT)-to-airway is a complex perinatal procedure performed in the case of potential postnatal airway obstruction. It requires an experienced multidisciplinary team and meticulous surgical planning based on fetal imaging. This report describes the use of EXIT-to-airway for a large cervical teratoma with extension into the mediastinum.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
August 2025
Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Objective: Amniotic fluid volume, measured in terms of the amniotic fluid index (AFI), is used widely in prenatal care to assess fetal health and development. We investigated whether distinct longitudinal AFI trajectories exist during pregnancy and their association with fetal growth.
Methods: This secondary analysis of a randomized controlled trial included singleton pregnancies without pre-existing or gestational diabetes mellitus that received prenatal care at National Taiwan University Hospital in Taipei and its Hsin-Chu Branch in Hsinchu, Taiwan.