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In artificial intelligence, it is crucial for pattern recognition systems to process data with uncertain information, necessitating uncertainty reasoning approaches such as evidence theory. As an orderable extension of evidence theory, random permutation set (RPS) theory has received increasing attention. However, RPS theory lacks a suitable generation method for the element order of permutation mass function (PMF) and an efficient determination method for the fusion order of permutation orthogonal sum (POS). To solve these two issues, this paper proposes a reasoning model for RPS theory, called random permutation set reasoning (RPSR). RPSR consists of three techniques, including RPS generation method (RPSGM), RPSR rule of combination, and ordered probability transformation (OPT). Specifically, RPSGM can construct RPS based on Gaussian discriminant model and weight analysis; RPSR rule incorporates POS with reliability vector, which can combine RPS sources with reliability in fusion order; OPT is used to convert RPS into a probability distribution for the final decision. Besides, numerical examples are provided to illustrate the proposed RPSR. Moreover, the proposed RPSR is applied to classification problems. An RPSR-based classification algorithm (RPSRCA) and its hyperparameter tuning method are presented. The results demonstrate the efficiency and stability of RPSRCA compared to existing classifiers.
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http://dx.doi.org/10.1109/TPAMI.2024.3438349 | DOI Listing |
Br J Dermatol
September 2025
Population Health Program, QIMR Berghofer, Brisbane, Australia.
Background: Sunscreen reduces vitamin D production in experimental studies. It is uncertain whether this translates to 'real-world' settings.
Objectives: We aimed to dtermine if routinely applying high-SPF sunscreen for one year reduces serum 25-hydroxyvitamin D [25(OH)D] concentration.
Front Oncol
August 2025
Department of Radiation Oncology, Gazi University School of Medicine, Ankara, Türkiye.
Background: Personalized medicine has transformed disease management by focusing on individual characteristics, driven by advancements in genome mapping and biomarker discoveries.
Objectives: This study aims to develop a predictive model for the early detection of treatment-related cardiac side effects in breast cancer patients by integrating clinical data, high-sensitivity Troponin-T (hs-TropT), radiomics, and dosiomics. The ultimate goal is to identify subclinical cardiotoxicity before clinical symptoms manifest, enabling personalized surveillance strategies.
Lancet Infect Dis
September 2025
The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Background: Based on results from preclinical and clinical studies, a five-drug combination of isoniazid, rifapentine, pyrazinamide, ethambutol, and clofazimine was identified with treatment shortening potential for drug-susceptible tuberculosis; the Clo-Fast trial aimed to determine the efficacy and safety of this regimen. We compared 3 months of isoniazid, rifapentine, pyrazinamide, ethambutol, and clofazimine, administered with a clofazimine loading dose, to the standard 6 month regimen of isoniazid, rifampicin, pyrazinamide, and ethambutol in drug-susceptible tuberculosis.
Methods: Clo-Fast was a phase 2c open-label trial recruiting participants at six sites in five countries.
Lancet
September 2025
Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea. Electronic address:
Background: The optimal timing of complete revascularisation for patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease remains unclear. We aimed to assess whether immediate complete revascularisation was non-inferior to staged complete revascularisation during the index admission.
Methods: We conducted an open-label, randomised, non-inferiority trial at 14 hospitals in South Korea.
JAMA Netw Open
September 2025
Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas Health Science Center at Houston, Houston.
Importance: Predicting treatment outcomes for internalizing psychopathologies (IPs), such as depression and anxiety, holds promise for advancing precision medicine. The extent to which whole-brain functional connectivity (FC) can predict treatment responses for patients with IPs across different therapeutic modalities remains unclear.
Objective: To examine whether pretreatment FC patterns predict multidimensional treatment outcomes in patients with IPs and whether predictive performance generalizes across diagnoses and treatment modalities.