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http://dx.doi.org/10.1245/s10434-024-16010-4 | DOI Listing |
Top Magn Reson Imaging
October 2025
BIOSPACE LAB, Nesles-la-Vallée, France.
Aims: Cardiac tumors are aggressive and asymptomatic in early stages, causing late diagnosis and locoregional metastasis. Currently, the standard of care uses gadolinium-based contrast agents for MRI, and the associated hypersensitivity reactions are a significant concern, such as gadolinium deposition disease. In addition, the proximity of cardiac lesions closer to vital structures complicates surgical interventions.
View Article and Find Full Text PDFJ Refract Surg
September 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Purpose: To evaluate axis-dependent visual and refractive outcomes of small incision lenticule extraction (SMILE) in patients with interocular astigmatic axis discordance.
Methods: Seventy-five patients (150 eyes) with interocular astigmatic axis discordance were included in the study. Based on interocular axis combinations, patients were stratified into three cohorts: with-the-rule (WTR)/against-the-rule (ATR) (n = 19), WTR/oblique astigmatism (OA) (n = 39), and ATR/OA (n = 17).
J Biopharm Stat
September 2025
Biostatistics and Research Decision Sciences, Merck & Co. Inc., North Wales, Pennsylvania, USA.
A randomized clinical trial with multiple experimental groups and one common control group is often used to speed up development to select the best experimental regimen or to increase the chance of success of clinical trials. Most of the time, multiple dose levels of an experimental drug or multiple combinations of one experimental drug with other drugs comprise multiple experimental groups. Because the experimental drug appears in multiple comparisons with a shared control group, multiple testing adjustments to control the family-wise type I error rate are needed.
View Article and Find Full Text PDFBMC Pulm Med
September 2025
Department of Anesthesiology and Pain Medicine, The Affiliated Hospital of Jiaxing University, Zhejiang Province, Jiaxing, China.
Mol Psychiatry
September 2025
Department of Psychology, Seoul National University, Seoul, South Korea.
A family history of depression is a well-documented risk factor for offspring psychopathology. However, the genetic mechanisms underlying the intergenerational transmission of depression remain unclear. We used genetic, family history, and diagnostic data from 11,875 9-10 year-old children from the Adolescent Brain Cognitive Development study.
View Article and Find Full Text PDF