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Objective: Psoriatic arthritis (PsA) is a heterogenous condition with musculoskeletal and skin manifestations. The physician global visual analog scale (VAS) is an important component of many composite scores used in clinical trials and observational studies. Currently, no training material exists to standardize this assessment.
Methods: The Psoriatic Arthritis Validation of Physician Global VAS (PAVLOVAS) project describes the development of a novel training infographic with stakeholder involvement, which was then evaluated in a Latin square design in which 20 patients with PsA were assessed by 10 clinicians. For each group of 10 patients, 5 assessors conducted traditional assessment (consisting of 66/68-joint count, body surface area, Leeds Enthesitis Index, and dactylitis and nail counts) and 5 assessors conducted a standardized, thorough general examination informed by the infographic. Assessors switched assessment type between groups. The 3-item (3VAS) and 4VAS informed by traditional and infographic methods were compared, alongside other composite scores.
Results: There was strong agreement between traditional and infographic physician global VAS (intraclass correlation coefficient [ICC] 0.69, = 0.01). This improved to very strong agreement when incorporated into the 3VAS (ICC 0.99, < 0.001) and 4VAS (ICC 0.99, < 0.001). The duration of assessment was significantly less for the infographic vs traditional groups (6.5 vs 7.8 mins, < 0.001). There was moderately high agreement between the 3VAS and 4VAS categories of disease activity, with the same categories defined by Psoriatic Arthritis Disease Activity Score (PASDAS) and Disease Activity Index for Psoriatic Arthritis (DAPSA; χ 17.0, = 0.049).
Conclusion: Our group developed and validated a novel training infographic that informs a briefer assessment of the physician global VAS than traditional assessments. This tool has potential applications in training and routine clinical practice.
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http://dx.doi.org/10.3899/jrheum.2024-0152 | DOI Listing |
Cureus
August 2025
College of Medicine, King Saud University, Riyadh, SAU.
Background Subclinical hypothyroidism (SCH) in pregnancy poses serious maternal and fetal risks, including miscarriage, gestational diabetes, and neurodevelopmental impairment. Despite clear international guidelines like those from the American Thyroid Association (ATA), global practice remains inconsistent. In Saudi Arabia, where SCH prevalence among pregnant women is notably high (13%), there is limited national data on how closely physicians follow these guidelines.
View Article and Find Full Text PDFCureus
August 2025
Midwifery Department, University of West Attica, Athens, GRC.
Cardiopulmonary resuscitation (CPR) is a critical, life-saving intervention. In pregnant women, unique anatomical and physiological changes require adaptations to standard CPR protocols to ensure optimal outcomes for both mother and fetus, emphasizing the need for universal awareness and standardized training across diverse healthcare systems globally. Despite the high-risk nature of maternal cardiac arrest, evidence suggests that many healthcare professionals may not be adequately prepared to respond effectively.
View Article and Find Full Text PDFClin Rheumatol
September 2025
Immunology Market Access, Johnson & Johnson, Horsham, PA, USA.
Introduction/objective: Oral glucocorticoids (OGC) are conventionally used as first-line treatment for dermatomyositis (DM) and polymyositis (PM). This study evaluated clinical and economic outcomes associated with long-term (LT) OGC use in DM/PM.
Methods: Adults with ≥ 2 medical claims of DM/PM 30‒365 days apart from January 1, 2016, to December 31, 2022, and ≥ 1 diagnosis code of a physician specialty of interest were selected from the MarketScan Commercial and Medicare Supplemental databases.
Int Urol Nephrol
September 2025
Department of Urology, Brigham and Women's Hospital, Harvard Medical School, 45 Francis St, ASB II-3, Boston, MA, 02115, USA.
Background: With the advancement of MR-based imaging, prostate cancer ablative therapies have seen increased interest to reduce complications of prostate cancer treatment. Although less invasive, they do carry procedural risks, including rectal injury. To date, the medicolegal aspects of ablative therapy remain underexplored.
View Article and Find Full Text PDFOne in five adolescents (10-19) live in sub-Saharan Africa. Despite the availability of policies targeted at this age group, policy formulation, implementation, and gains in adolescent health continue to be underwhelming. Actors or stakeholders are architects of policy, bringing their ideological values, interests, power, and positions to policy formulation and implementation and thus influencing the policy process.
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