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Background: Nowadays, we observe a growing interest in conduction system pacing (CSP). Therefore, we expect the number of patients with CSP to increase significantly in the coming years. However, there is a lack of large data on transvenous lead extraction (TLE) procedures of CSP leads, particularly His bundle pacing (HBP) leads in the adult population.
Aims: This study aimed to present the experience of performing TLE procedures in patients with CSP leads using a non-stylet-driven Medtronic 3830 lead in two tertiary lead extraction centers in Poland.
Methods: A prospective analysis of the records involved of all patients with HBP leads who underwent TLE from October 2011 to November 2023.
Results: The study involved 38 patients, at a median (interquartile range [IQR]) age of 69.7 (65.6-76.0) years, 8 of whom were female (21.1%). The median (IQR) lead dwell time was 15.5 (8.7-19.8) months. Thirty leads were removed using simple traction, while 8 leads required mechanical extraction tools. All leads with lead dwell time over 42 months required mechanical extraction tools. The median (IQR) fluoroscopy time was 1.03 (0.07-11.5) min. There were no intra-procedural major or minor complications. Radiological and clinical success was achieved in 100% of targeted CSP leads.
Conclusion: TLE from the His bundle and left bundle branch region is a safe and effective procedure, with no lasting damage to the His-Purkinje system. Successful re-implantation of the lead in the His-Purkinje conduction system is possible in most cases.
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http://dx.doi.org/10.33963/v.phj.101556 | DOI Listing |
Int J Cancer
September 2025
Laboratory for Computational Physiology, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
The rise in cancer patients could lead to an increase in intensive care units (ICUs) admissions. We explored differences in treatment practices and outcomes of invasive therapies between patients with sepsis with and without cancer. Adults from 2008 to 2019 admitted to the ICU for sepsis were extracted from the databases MIMIC-IV and eICU-CRD.
View Article and Find Full Text PDFJ Integr Neurosci
August 2025
School of Computer Science, Guangdong Polytechnic Normal University, 510665 Guangzhou, Guangdong, China.
Background: Emotion recognition from electroencephalography (EEG) can play a pivotal role in the advancement of brain-computer interfaces (BCIs). Recent developments in deep learning, particularly convolutional neural networks (CNNs) and hybrid models, have significantly enhanced interest in this field. However, standard convolutional layers often conflate characteristics across various brain rhythms, complicating the identification of distinctive features vital for emotion recognition.
View Article and Find Full Text PDFStruct Heart
September 2025
The Carl and Edyth Lindner Research Center at the Christ Hospital, Cincinnati, Ohio, USA.
Severe, untreated tricuspid regurgitation is associated with worse clinical outcomes. While isolated tricuspid valve (TV) surgery has been linked to poor long-term outcomes, transcatheter TV therapies, including edge-to-edge repair and transcatheter tricuspid valve replacement (TTVR), have emerged as effective alternatives and have been shown to improve outcomes, leading to their regulatory approval in the United States. Conduction system abnormalities are commonly seen among patients undergoing TTVR due to the close proximity of the atrioventricular node and the His bundle to the TV annulus.
View Article and Find Full Text PDFPain Res Manag
September 2025
Department of Thoracic and Cardiovascular Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Pectus excavatum is a common congenital chest wall deformity that can lead to significant cardiopulmonary compression and psychological distress. The minimally invasive Nuss procedure is the standard treatment, but it often results in severe postoperative pain. Effective perioperative pain management is essential to enhance recovery and improve patient outcomes.
View Article and Find Full Text PDFEur Heart J Case Rep
September 2025
GNH Klinikum Kassel, Center for Cardiac Care, Mönchebergstraße 41-45, Kassel 34125, Germany.
Background: Pacemaker implantation has become a routine procedure in contemporary cardiology. Several possible complications during and after the procedure have been described, with this article focusing on the rare complication and the prevention of left-sided lead placement after arterial puncture.
Case Summary: A 90-year-old female patient was admitted to our hospital due to recurrent transient ischaemic attacks following a dual-chamber pacemaker implantation six weeks earlier.