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Article Abstract

Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. For the 2021-22 and 2022-23 influenza seasons, 26 forecasting teams provided national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one-to-four weeks ahead. Forecast skill is evaluated using the Weighted Interval Score (WIS), relative WIS, and coverage. Six out of 23 models outperform the baseline model across forecast weeks and locations in 2021-22 and 12 out of 18 models in 2022-23. Averaging across all forecast targets, the FluSight ensemble is the 2 most accurate model measured by WIS in 2021-22 and the 5 most accurate in the 2022-23 season. Forecast skill and 95% coverage for the FluSight ensemble and most component models degrade over longer forecast horizons. In this work we demonstrate that while the FluSight ensemble was a robust predictor, even ensembles face challenges during periods of rapid change.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11282251PMC
http://dx.doi.org/10.1038/s41467-024-50601-9DOI Listing

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Article Synopsis
  • Accurate forecasts improve public health responses to seasonal influenza, with 26 teams providing predictions for hospital admissions in 2021-22 and 2022-23.
  • Six out of 23 models performed better than the baseline in 2021-22, while 12 out of 18 models did so in 2022-23, with the FluSight ensemble being highly ranked in both seasons.
  • Despite its accuracy, the FluSight ensemble and other models struggled with longer forecast periods, especially during times of rapid change in influenza patterns.
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Combining predictions from multiple models into an ensemble is a widely used practice across many fields with demonstrated performance benefits. Popularized through domains such as weather forecasting and climate modeling, multi-model ensembles are becoming increasingly common in public health and biological applications. For example, multi-model outbreak forecasting provides more accurate and reliable information about the timing and burden of infectious disease outbreaks to public health officials and medical practitioners.

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Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. Forecasting teams were asked to provide national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one through four weeks ahead for the 2021-22 and 2022-23 influenza seasons. Across both seasons, 26 teams submitted forecasts, with the submitting teams varying between seasons.

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