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http://dx.doi.org/10.1016/j.asjsur.2024.07.084 | DOI Listing |
Am J Clin Pathol
September 2025
Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Objective: Choline transporter (ChT) immunohistochemistry (IHC) is a new ancillary test that aids in the diagnosis of Hirschsprung disease in newborns and infants. The behavior of this stain in older children (greater than 1 year of age) with chronic constipation, where Hirschsprung disease is clinically unlikely, has not been investigated. The aim of our study was to determine the behavior of ChT IHC in rectal biopsies performed on older children with chronic constipation.
View Article and Find Full Text PDFEndoscopy
December 2025
Department of Endoscopy, Aichi Cancer Center Hospital, Nagoya, Japan.
Khirurgiia (Mosk)
September 2025
National Medical Research Center of Oncology, Rostov-on-Don, Russia.
Objective: To study the results of treatment of cancer in tubular villous adenomas.
Material And Methods: A retrospective analysis included 51 patients with cTis-T1N0M0 between 02.2019 and 09.
Medicine (Baltimore)
September 2025
Anesthesiology Department, Southern Central Hospital of Yunnan Province (First People's Hospital of Honghe State), Mengzi, Yunnan Province, China.
Rationale: Ureteral stricture is a complex urological condition often requiring surgical intervention. Autologous tissue grafts, such as lingual mucosa, have emerged as a promising option for reconstruction due to their favorable biocompatibility and vascularity. However, reports on complications associated with these techniques remain limited.
View Article and Find Full Text PDFColorectal Dis
September 2025
Department of Surgery, Sheffield Teaching Hospitals, Sheffield, UK.
Aim: Controversy exists over whether surgical technique can reduce recurrence following Crohn's resection. This study compares the rate of endoscopic recurrence after different approaches to mesenteric excision (extended/close) and anastomosis (Kono-S/standard of care) in adult patients undergoing ileocolic resection for primary or recurrent Crohn's disease.
Method: MEErKAT is a UK multicentre, 2 × 2 factorial, randomised, controlled, open-label superiority trial where participants (target sample size = 308) are blinded and centrally randomised (1:1:1:1) to one of four groups: (1) Kono-S + extended mesenteric resection.