98%
921
2 minutes
20
Paraduodenal pancreatitis (PP), also known as groove pancreatitis (GP), is a rare and distinct variant of chronic pancreatitis and presents significant diagnostic and therapeutic challenges. This comprehensive case study explores a 54-year-old male patient's journey, highlighting the intricate relationship between clinical presentation, diagnostic modalities, and management strategies. Despite a history of smoking and alcohol consumption, the diagnosis of PP was primarily reliant on advanced imaging techniques, including computed tomography and magnetic resonance imaging, which revealed characteristic findings of GP. The case underscores the importance of a high index of suspicion and a step-up approach to management, starting with conservative treatment and progressing to surgical intervention as necessary. This study contributes to the growing body of knowledge on PP, emphasizing the need for awareness and understanding of this rare condition to improve patient outcomes.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11272387 | PMC |
http://dx.doi.org/10.7759/cureus.63149 | DOI Listing |
Cell Mol Biol (Noisy-le-grand)
September 2025
Department of Biology, College of Education for Pure Sciences, University of Kerbala, Kerbala, Iraq.
Gastric cancer is one of the causes of deaths related to cancer across the globe and both genetic and environmental factors are the most prominent. Causes of its pathogenesis. This paper researches the expression of the C-FOS gene.
View Article and Find Full Text PDFInt J Biometeorol
September 2025
Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing, 100101, China.
Plant viewing activities, which encompass the enjoyment of seasonal plant phenomena such as flowering and autumn leaf coloration, have become popular worldwide. Plant viewing activities are increasingly challenged by climate change, as key components like plant phenology and climate comfort are highly sensitive to global warming. However, few studies have explored the impact of climate change on viewing activities, particularly from an integrated, multi-factor perspective.
View Article and Find Full Text PDFVestn Oftalmol
September 2025
Chelyabinsk Regional Clinical Hospital, Chelyabinsk, Russia.
Rosacea is a chronic inflammatory dermatosis, one manifestation of which involves pathological processes in various ocular structures. The most severe form is rosacea-associated keratitis. Given the multifactorial etiology and pathogenesis, this condition remains unpredictable and resistant to treatment.
View Article and Find Full Text PDFBrief Bioinform
August 2025
State Key Laboratory of Animal Biotech Breeding, College of Biological Sciences, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China.
The systematic identification of human-virus protein-protein interactions (PPIs) is a critical step toward elucidating the underlying mechanisms of viral infection, directly informing the development of targeted interventions against existing and emerging viral threats. In this work, we presented DeepGNHV, an end-to-end framework that integrated a pretrained protein language model with structural features derived from AlphaFold2 and leveraged graph attention networks to predict human-virus PPIs. In comparison to other state-of-the-art approaches, DeepGNHV exhibited superior predictive performance, especially when applied to viral proteins absent from the training process, indicating its strong generalization capability for detecting newly emerging virus-related PPIs.
View Article and Find Full Text PDF