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For the first time, we suggest using leaf extract from Ocimum americanum as the economically viable bio-fabrication of copper nanomaterials. The residuals of leaf extract bio-capping provide the stability of the nanomaterials in-situ. UV-Vis and XRD confirmed the formation, with the UV-Vis spectrum of Cu-NMs revealing a surface plasmon resonance characteristic peak at 350 nm. FT-IR analysis was employed to examine the functional groups. FE-SEM with EDX was used to assess the morphology and carry out an elemental analysis of the nanomaterials. Diffusion and MTT assays were used to study the antimicrobial and anticancer activities. The synthesized copper nanomaterials exhibited in-vitro cytotoxicity against human skin cancer (A431) cell lines. Green nanomaterial was examined against the methylene blue dye, photodegradation was reduced by up to 90.6% within 50 minutes. The copper nanomaterials synthesized in our study exhibit promising applications in biomedicine and environmental pollution research.
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http://dx.doi.org/10.1002/bio.4831 | DOI Listing |
Beilstein J Nanotechnol
August 2025
Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.
The preparation of multimodal nanoparticles by capping magnetic iron oxide nanoparticles (IONPs) with functional organic molecules is a major area of research for biomedical applications. Conjugation reactions, such as carbodiimide coupling and the highly selective class of reactions known as "click chemistry", have been instrumental in tailoring the ligand layers of IONPs to produce functional biomedical nanomaterials. However, few studies report the controls performed to determine if the loading of molecules onto IONPs is due to the proposed coupling reaction(s) employed, or some other unknown interaction with the IONP surface.
View Article and Find Full Text PDFDalton Trans
September 2025
Department of Chemistry, Istanbul Technical University, Maslak, Istanbul, 34469, Türkiye.
A novel phthalonitrile derivative (a) containing three functional groups (hexyl, aminated ester, phenoxy) was synthesized and subsequently cyclotetramerized in the presence of the corresponding metal chloride salts to obtain hexadeca-substituted metal {M = Cu(II) and Co(II)} phthalocyanines (b and c). The water-soluble phthalocyanines (d and e) were prepared by treating the newly synthesized complexes (b and c) with methyl iodide. Moreover, gold nanoparticles (1) and silver nanoparticles (2) were prepared, and their surfaces were modified with quaternary phthalocyanines (d and e).
View Article and Find Full Text PDFNanoscale
September 2025
Department of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, 117575, Singapore.
Electromagnetic pollution poses significant risks to electronic devices and human health, highlighting the need for mechanically robust, lightweight, and cost-effective electromagnetic interference (EMI) shielding materials. 3D-printed structures with nanomaterial-engineered surfaces offer a promising method for tailoring mechanical and electrical properties through multiscale design. Herein, we present a facile strategy for fabricating lightweight and flexible EMI shielding structures by chemical deposition of nanostructured metal coatings onto 3D-printed polymeric substrates.
View Article and Find Full Text PDFJ Appl Toxicol
September 2025
Chair for DNA Research, Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Metal oxide nanoparticles are employed in various applications such as medicine, environmental remediation, molecular sensing, and drug delivery. However, large-scale commercial production and the use of smaller-sized nanoparticles increase the potential risk of toxicity to humans. Therefore, there is an urgent need to investigate the toxicity of nanomaterials.
View Article and Find Full Text PDFMikrochim Acta
September 2025
Shenyang Pharmaceutical University, 103 Wenhua Road Shenhe District, Shenyang, 110016, Liaoning, People's Republic of China.
A novel dual-mode sensing system integrating a magnetic core-shell CuFeO/Cu/MnO nanozyme with a stimuli-responsive agarose-deep eutectic solvent hydrogel (DES-Aga) is reported. The nanozyme exhibits exceptional oxidase-like activity, characterized by a low Michaelis constant (K = 0.14 mM) and high catalytic efficiency (V = 1.
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