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Subepithelial gastric tumors are a diagnostic challenge. Endoscopic ultrasound allows differentiation. Lesions originating from the submucosal layer can be resected using endoscopic submucosal dissection (ESD). Surgery or endoscopic full-thickness resection (EFTR) techniques are alternatives. We present a patient with an 11 × 8 mm submucosal tumor in the gastric antrum suggestive of a gastrointestinal stromal tumor, originating from the muscularis propria. Eventually endoscopic resection was performed, combining ESD and EFTR (hybrid ESD-EFTR). Contrary to expectations, histology revealed a gastric schwannoma. This case illustrates an efficient and safe endoscopic hybrid technique for the removal of submucosal gastric lesions.
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http://dx.doi.org/10.14309/crj.0000000000001440 | DOI Listing |
Surgical pathologists who examine gastric biopsies must triage exuberant lymphoid infiltrates for hematopathology consultation, a task that should account for resource and time utilization. We assembled all cases of chronic gastritis sent by surgical pathologists to hematopathology due to concern for low-grade lymphoma over a 4-year interval. The cases were ultimately classified as reactive (n=37), atypical (n=9), or lymphoma (n=18).
View Article and Find Full Text PDFAm J Clin Pathol
September 2025
Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
Objective: Choline transporter (ChT) immunohistochemistry (IHC) is a new ancillary test that aids in the diagnosis of Hirschsprung disease in newborns and infants. The behavior of this stain in older children (greater than 1 year of age) with chronic constipation, where Hirschsprung disease is clinically unlikely, has not been investigated. The aim of our study was to determine the behavior of ChT IHC in rectal biopsies performed on older children with chronic constipation.
View Article and Find Full Text PDFSurg Endosc
September 2025
Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Background And Aims: Traditional endoscopic full-thickness resection (EFTR) involves complete removal of the lesion followed by defect closure. The separated resection and closure technique results in mucosal eversion and misalignment of the muscularis propria layers, making reliable closure difficult. Here, we developed an innovative "cut-and-seal-as-you-go" technique, "Zipper-EFTR" and evaluated the feasibility and safety of the new technique.
View Article and Find Full Text PDFEndoscopy
December 2025
Department of Gastroenterology and Hepatology, Yokohama City University School of Medicine Graduate School of Medicine, Yokohama, Japan.
Dig Dis Sci
September 2025
Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Zhengzhou University, No.1 Jianshe East Road, Zhengzhou, 450052, Henan, China.