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BACKGROUND Pyogenic spondylodiscitis is infection of the intervertebral disc or discs and the adjacent vertebrae. This retrospective study aimed to compare the effectiveness of percutaneous endoscopic lumbar debridement (PELD) versus posterior lumbar interbody fusion (PLIF) in 40 patients with pyogenic spondylodiscitis (PSD). MATERIAL AND METHODS Medical records of patients who underwent PELD (n=18) or PLIF (n=22) for PSD between 2018 and 2023 were reviewed. The recorded outcomes encompassed surgical duration, intraoperative blood loss, Oswestry Disability Index (ODI) measurements, Visual Analog Scale (VAS) assessments, C-reactive protein (CRP) levels, duration of hospitalization, erythrocyte sedimentation rate (ESR), American Spinal Injury Association (ASIA) grading, lumbar sagittal parameters, and the incidence of complications. RESULTS The PELD group had shorter surgical duration, less intraoperative blood loss, and shorter length of hospital stay compared to the PLIF group (P<0.01). At the last follow-up, both groups had significant improvement in ESR, CRP levels, and ASIA classification (P<0.001), but there was no significant difference between the 2 groups (P>0.05). The PELD group had lower ODI and VAS ratings at 1 month and 3 months, respectively (P<0.01). The PLIF group had significant improvements in intervertebral space height and lumbar lordosis angle (P<0.01). CONCLUSIONS Both PLIF and PELD surgical approaches demonstrate adequate clinical efficacy in the treatment of monosegmental PSD. PLIF can better ensure more spinal stability than PELD, but PELD offers advantages such as reduced minimal surgical trauma, shorter operative duration, and faster recovery after surgery.
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http://dx.doi.org/10.12659/MSM.943176 | DOI Listing |
Sci Rep
September 2025
Spine Center and Department of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 82, Gumi-ro 173 Beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, 13620, Republic of Korea.
Thoracolumbar infectious spondylodiscitis is a serious condition that often requires surgical intervention if conservative treatment fails. Debridement and drainage are crucial in removing infected tissues and achieving adequate control of the source of infection. In this study, we aimed to evaluate the surgical outcomes of microscopic debridement in patients with thoracolumbar spondylodiscitis.
View Article and Find Full Text PDFJ Clin Med
August 2025
Swedish Neuroscience Institute, Swedish Medical Center, 550 17th Avenue, Suite 500, Seattle, WA 98122, USA.
Spondylodiscitis is a growing infectious condition with significant morbidity. The impact of multifocal involvement remains understudied. This study compared 90-day all-cause readmission rates between patients with solitary versus multifocal spondylodiscitis and identified the associated risk factors.
View Article and Find Full Text PDFEur Spine J
August 2025
Goethe University Frankfurt, University Hospital, Institute of Neuroradiology, Frankfurt am Main, Germany.
Objectives: Differentiating between pyogenic spondylodiscitis (SD) and degenerative disc disease (DDD) can be challenging due to overlapping clinical and radiological features. However, accurate distinction is critical to ensure timely and appropriate treatment and to avoid serious complications. This study aimed to identify imaging features that reliably distinguish pyogenic SD from DDD, including its erosive subtype, in clinical practice.
View Article and Find Full Text PDFClin Case Rep
August 2025
Spinal infectious diseases are difficult to diagnose and treat; we reported a case of pyogenic spondylitis misdiagnosed as terminal discitis and successfully treated. The application of metagenomic next-generation sequencing technology holds promise in greatly improving diagnostic efficiency.
View Article and Find Full Text PDFSpine Surg Relat Res
July 2025
Department of Orthopaedic Surgery, Hokkaido University Hospital, Hokkaido, Japan.
Introduction: Delayed diagnosis and therapy initiation for pyogenic spondylitis can have severe and fatal consequences. Early diagnosis and intervention are crucial in the treatment of pyogenic spondylitis. This multicenter cross-sectional study with prospective case series aimed to identify factors influencing the time from symptom onset to the diagnosis of pyogenic spondylitis.
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