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http://dx.doi.org/10.1016/j.jcct.2024.07.008 | DOI Listing |
Int J Cardiovasc Imaging
September 2025
Department of Cardiology, Bern University Hospital, University of Bern, Bern, Switzerland.
Purpose: A five-grade severity scheme has been introduced for echocardiographic grading of tricuspid regurgitation (TR). Although higher TR grades have been associated with worse prognosis, it is unknown whether they can help determining patient eligibility for transcatheter tricuspid valve interventions (TTVI) and correspond to different anatomical phenotypes. The aim of our study was to investigate the relationship between TR severity and tricuspid valve (TV) anatomy and determine the screening failure rate for TTVI.
View Article and Find Full Text PDFEur J Radiol
August 2025
Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. No.197 Ruijin Er Road Shanghai, Shanghai CN200025, China. Electronic address:
Rationale And Objectives: Advances in computed tomography (CT) have enabled myocardial extracellular volume (ECV) quantification, but the optimal post-contrast timing for CT-derived ECV remains undefined. In this preclinical study using a swine model, we aimed to determine the optimal post-contrast acquisition time for photon-counting CT (PCCT)-derived ECV using cardiac magnetic resonance (CMR) as the reference standard.
Materials And Methods: Twenty-three CMR and PCCT scans were performed on infarcted swine, and nine scans on healthy controls.
Eur Heart J Cardiovasc Imaging
August 2025
Heart and Vascular Centre, Semmelweis University, Budapest, Hungary.
Aims: Inorganic pyrophosphate (PPi) is an endogenous inhibitor of soft-tissue calcification. A disturbed equilibrium between pro- and anti-mineralization agents, like extracellular phosphate (Pi) and PPi, have been implicated in the mechanism of aortic valve calcification (AVC). We aimed to investigate the association of the plasma PPi concentration and Pi/PPi ratio with the degree AVC in cardiovascular patients.
View Article and Find Full Text PDFEur J Prev Cardiol
August 2025
Sorbonne Université, Laboratoire d'Imagerie Biomédicale, Inserm, CNRS, Paris, France.
J Biomech Eng
August 2025
National Heart and Lung Institute, Imperial College London, London W12 0NN, UK & The Alan Turing Institute, The British Library, London NW1 2DB, UK.
Cardiovascular diseases are the leading cause of death. Clinical data used to decide treatment are hard to integrate and interpret, making optimal treatment selection difficult. Personalised models can be used to integrate clinical data into a physics and physiology-constrained framework, but their clinical application faces limitations due to complex calibration and validation.
View Article and Find Full Text PDF