98%
921
2 minutes
20
This retrospective clinical study aimed to assess dental pulp tissue reactions to direct and indirect pulp capping after 10 years of follow-up. A total of 276 permanent teeth with deep carious lesions were evaluated and divided into five groups: Group (1), direct pulp capping with Mineral Trioxide Aggregate cement; Group (2), direct pulp capping with a resin-based glass ionomer; Group (3), direct pulp capping with TheraCal; Group (4), indirect pulp capping with a three-step total-etch adhesive system; and Group (5), indirect pulp capping with a two-step self-etch adhesive system. A 72.5% success rate was achieved overall. A statistically significant difference was found when comparing direct and indirect pulp capping with a success rate of 23.8% and 93.8%, respectively. For direct pulp-capping procedures, the area of pulp exposure was correlated with pulp necrosis ( = 0.035), while bleeding after exposure appeared independent ( = 0.053). Patient age was significantly related to the maintenance of pulp vitality ( = 0.013). A statistically significant correlation between the pulp-capping material and the occurrence of pulp necrosis was discovered ( = 0.017). For the indirect pulp-capping treatments, a significant correlation between patient age ( = 0.021) and the adhesive system ( = 0.019) with pulp necrosis was described. The pulp-capping material, patient age, and the width of the pulp exposure before the procedure should be carefully considered when performing direct pulp-capping treatments. The performance of the etch-and-rinse adhesive systems was superior to the self-etch system during the indirect pulp-capping procedures.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11242907 | PMC |
http://dx.doi.org/10.3390/jcm13133962 | DOI Listing |
Biomaterials
August 2025
Department of Prosthodontics, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration & Shandong Provincial Clinical Research Cen
Dental tissue regeneration is often challenged by the hostile inflammatory microenvironment and the dysfunction of reparative cells due to oxidative stress. This study presents a reactive oxygen species (ROS)-scavenging nanozyme induced by ligand-to-metal charge transfer, engineered as a multifunctional capping material through the in situ growth of copper-gallate (CuGA) on hydroxyapatite nanofibers (HAFs). The obtained CuGA@HAF demonstrates superior ROS-scavenging capacity through its multi-enzyme mimetic activity, effectively rescuing the function of dental pulp stem cells (DPSCs) under oxidative stress by restoring mitochondrial homeostasis.
View Article and Find Full Text PDFRestor Dent Endod
August 2025
Department of Oral Biology, Saveetha Dental College, Saveetha Institute of Science and Technology, Chennai, India.
Objectives: The aim of this study was to create a rapid admixture of mineral trioxide aggregate (MTA) and silver nanoparticles (AgNPs) for chairside use in clinical settings to remediate the challenges associated with root canal treatment and pulp capping.
Methods: Synthesized AgNPs at ratios of 10 and 25% were added to commercially available MTA to create an admixture. The admixture was subjected to structural and morphological assessment using X-ray diffraction analysis (XRD), Fourier transform infrared (FT-IR) analysis, Raman spectroscopy, and scanning electron microscopy.
Cureus
July 2025
Department of Conservative Dentistry and Endodontics, DY Patil School of Dentistry, Navi Mumbai, IND.
The present systematic review and meta-analysis aimed to evaluate and compare the clinical efficacy of Mineral Trioxide Aggregate (MTA) and Biodentine (BD) as direct pulp capping materials in cariously exposed mature permanent teeth, focusing on outcomes such as pulp vitality preservation, dentin bridge formation, and complication rates, including tooth discoloration. A comprehensive literature search was conducted across PubMed, Scopus, Web of Science, and other dental databases following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The review protocol was registered in PROSPERO (CRD42023463513).
View Article and Find Full Text PDFACS Biomater Sci Eng
September 2025
Department of Chemical Engineering and Materials Science, Yuan Ze University, Taoyuan 320315, Taiwan.
Conventional clinical approaches for regenerative endodontic procedures, root canal therapy, and vital pulp therapy often lack sufficient antimicrobial efficacy, thereby increasing the risk of post-treatment apical periodontitis. To overcome this limitation, a series of antimicrobial powders (referred to as the AC series) was synthesized through a chemical reaction between tricalcium silicate (CS) powder and chitosan solution pretreated with acetic acid. Following this, the AC powders were subsequently physically blended with additional CS to enhance the mechanical properties, thereby developing a chitosan-based bioceramic composite, named the AC-C series.
View Article and Find Full Text PDFJ Dent
August 2025
Department of Endodontics, Recep Tayyip Erdoğan University, Turkey. Electronic address:
Objectives: This systematic review and network meta-regression (NMR) aimed to evaluate and compare the clinical effectiveness of various direct pulp capping (DPC) materials used in permanent teeth, incorporating follow-up duration as a covariate.
Materials And Methods: A comprehensive literature search was conducted across multiple databases, including PubMed, Cochrane Library, Scopus, and Web of Science, without language restrictions. Only randomized clinical trials comparing at least two DPC materials with a minimum follow-up of three months were included.