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Diseases are responsible for losses in livestock production by increasing animal mortality and reducing productivity. The administration of antibiotics can help mitigate these negative effects. However, inappropriate use can lead to severe complications, such as raising antibiotic resistance. The purpose of this study was to perform a comparative analysis of antibiotic use and disease frequency over four years, based on the size of dairy farms and the type of farm. The study covered a 4-year period and included medium dairy farms (20-50 cows, n = 13), large dairy farms (>250 cows, n = 8), and large beef farms (n = 8). The collected data involved antimicrobial use but also included farm demographics, animal health, disease frequency, and herd management practices. The criteria used to categorise antibiotics into groups A-D were based on the EMA guidelines. The carried-out study showed that the large dairy cattle farms had the highest antibiotic consumption (18.29 mg·PCU), due to the high frequency of diseases, and consequently, the treatment of calf (diarrhoea, lung inflammations) and cow diseases (general treatment and mastitis). Cattle on large beef farms suffer mainly from general diseases caused by maintenance and herd management conditions. The use of restrict antibiotics was, in some cases, unjustified (antibiotics for dry cow therapy). Future studies should consider a larger number of farms, taking into account the given direction of cattle production.
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http://dx.doi.org/10.3390/ani14131889 | DOI Listing |
Parasitol Int
September 2025
Immunoparasitology Laboratory, Faculty of Veterinary Science-La Plata National University, La Plata, 1900 Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Ciudad Autónoma de Buenos Aires (C1425FQB), Argentina; Institute of Parasitology, University of Bern, Län
The apicomplexan protozoa Neospora caninum, Sarcocystis spp. and Toxoplasma gondii are worldwide distributed. Goat infections with these protozoans are frequent, although the relationship with milk production is unknown.
View Article and Find Full Text PDFNat Genet
September 2025
State Key Laboratory of Animal Biotech Breeding, National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction of Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, China Agricultural University, Beijing, China. su
Systematic characterization of the molecular states of cells in livestock tissues is essential for understanding the cellular and genetic mechanisms underlying economically and ecologically important physiological traits. Here, as part of the Farm Animal Genotype-Tissue Expression (FarmGTEx) project, we describe a comprehensive reference map including 1,793,854 cells from 59 bovine tissues in calves and adult cattle, spanning both sexes, which reveals intra-tissue and inter-tissue cellular heterogeneity in gene expression, transcription factor regulation and intercellular communication. Integrative analysis with genetic variants that underpin bovine monogenic and complex traits uncovers cell types of relevance, such as spermatocytes, responsible for sperm motility and excitatory neurons for milk fat yield.
View Article and Find Full Text PDFJ Dairy Sci
September 2025
Department of Food Quality and Safety, College of Food Science and Engineering, Jilin University, Changchun, China. Electronic address:
This review article presents an overview of the structure-function characteristics and extensive applications of complexes formed between lactoferrin (Lf) and various bioactive compounds. Lactoferrin, a glycoprotein predominantly found in colostrum, possesses iron-binding capacity and exhibits a wide range of biological activities, including antibacterial, antiviral, antifungal, antiparasitic, anti-inflammatory, anticancer, and antitumor effects. Through complexation with proteins, phenolic compounds, polysaccharides, and other bioactive substances, the structural and functional properties of Lf are significantly improved, enhancing its potential applications in the food, pharmaceutical, cosmetic, and industrial sectors.
View Article and Find Full Text PDFJ Dairy Sci
September 2025
Department of Ruminant Science, Institute of Animal Sciences, The Volcani Institute, Rishon LeZion 7505101, Israel. Electronic address:
Several factors influence the effectiveness of forage in ruminant rations, including NDF content and the physical nature, fragility, digestibility, and more of the forage. Recently, several studies suggested using the undigestible NDF (uNDF) fraction as a possible approach to achieve a more precise ration. The objective of the current study was to reduce the forage content of the diet by using the in vitro forage uNDF for diet formulation and to determine the effects on production, rumen environment, and digestibility.
View Article and Find Full Text PDFJ Dairy Sci
September 2025
Department of Food Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853.
Clostridium tyrobutyricum is a spore-forming bacterium and is considered to be one of the main causative agents of late blowing defect (LBD) of hard and semi-hard cheeses. However, the spoilage potential of C. tyrobutyricum appears to be strain dependent.
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