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http://dx.doi.org/10.26599/1671-5411.2024.06.005 | DOI Listing |
Clin Transplant
September 2025
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Background: Liver transplantation is the definitive treatment for end-stage liver disease and some cancers. The use of livers from donors following pre-donation cardiac arrest (PDCA), especially with prolonged downtime duration, has been limited outside of the US due to fears over inferior outcomes from ischemic injury. However, PDCA may induce ischemic preconditioning, paradoxically improving post-transplant outcomes.
View Article and Find Full Text PDFCureus
August 2025
Anaesthesiology, Pholosong Regional Hospital, Johannesburg, ZAF.
Cardiac arrest in pregnancy is a rare event and poses a great risk to the mother and the fetus. A perimortem cesarean delivery (PMCD) is indicated within four minutes of cardiac arrest if the return of spontaneous circulation (ROSC) has not been achieved. This is a case of a 24-year-old pregnant woman who had a cardiac arrest and underwent a PMCD within six minutes.
View Article and Find Full Text PDFbioRxiv
August 2025
Department of Biological Sciences, Southern Methodist University, Dallas, TX.
The leading cause of epilepsy-related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure-induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms, providing a unified explanation for seizures and lethal arrhythmias. However, the relative contributions of brain-driven mechanisms, heart-intrinsic processes, and seizures to cardiac dysfunction in epilepsy remain unclear.
View Article and Find Full Text PDFJ Electrocardiol
August 2025
Cardiology, Government TD Medical College Alappuzha, Kerala, India.
We report an elderly woman who presented with cardiac arrest due to complete heart block. She developed progressive T-wave inversions in leads V3-V6 due to pacinginduced cardiac memory, accompanied by marked QTc prolongation. These repolarization abnormalities occurred despite normal electrolytes and non-obstructive coronary angiography and culminated in polymorphic ventricular tachycardia.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Faculty of Medicine, Palestine Polytechnic University, Hebron, West Bank, Palestine.
Rationale: Trisomy 18, often known as Edwards syndrome. It is a common chromosomal disorder characterized by the presence of an extra chromosome 18. Unfortunately, survival past the first year is quite rare, and there are only a few reports of individuals living long-term without needing corrective surgery.
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