Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

This is a process evaluation of a large UK-based randomised controlled trial (RCT) (n = 5602) evaluating the effectiveness of recommending an alcohol reduction app, Drink Less, compared with usual digital care in reducing alcohol consumption in increasing and higher risk drinkers. The aim was to understand whether participants' engagement ('self-reported adherence') and behavioural characteristics were mechanisms of action underpinning the effectiveness of Drink Less. Self-reported adherence with both digital tools was over 70% (Drink Less: 78.0%, 95% CI = 77.6-78.4; usual digital care: 71.5%, 95% CI = 71.0-71.9). Self-reported adherence to the intervention (average causal mediation effect [ACME] = -0.250, 95% CI = -0.42, -0.11) and self-monitoring behaviour (ACME = -0.235, 95% CI = -0.44, -0.03) both partially mediated the effect of the intervention (versus comparator) on alcohol reduction. Following the recommendation (self-reported adherence) and the tracking (self-monitoring behaviour) feature of the Drink Less app appear to be important mechanisms of action for alcohol reduction among increasing and higher risk drinkers.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217434PMC
http://dx.doi.org/10.1038/s41746-024-01169-7DOI Listing

Publication Analysis

Top Keywords

alcohol reduction
12
self-reported adherence
12
effectiveness drink
8
usual digital
8
digital care
8
increasing higher
8
higher risk
8
risk drinkers
8
mechanisms action
8
self-monitoring behaviour
8

Similar Publications

CuCo-Embedded Nitrogen-Doped Carbon as a Bifunctional Catalyst for Efficient Rechargeable Zinc-Ethanol/Air Batteries.

ACS Appl Mater Interfaces

September 2025

College of Chemistry and Chemical Engineering, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha 410081, China.

The oxygen evolution reaction (OER) in conventional zinc-air batteries (ZABs) involves a complex multielectron transfer process, leading to slow reaction kinetics, high charging voltage, and low energy efficiency. To address these limitations, a zinc-ethanol/air battery (ZEAB) system that strategically replaces the OER with the ethanol oxidation reaction (EOR) possessing a lower thermodynamic potential has been proposed. Herein, a bimetallic catalyst CuCo-embedded nitrogen-doped carbon (CuCo-20%-1), derived from a Cu/Co/Cd co-coordinated metal-organic precursor, is synthesized and exhibits an excellent performance for both EOR and ORR.

View Article and Find Full Text PDF

Increased alcohol intake and alcohol use disorder following bariatric surgery: potential mechanisms.

Physiol Behav

September 2025

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1399 Park Avenue, New York, NY, 10029, United States. Electronic address:

Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most effective weight loss procedures for severe obesity. However, there is recent evidence of increased alcohol intake and new onset alcohol use disorder (AUD) by 2 yr following both operations. Although the two surgeries differ anatomically, they lead to similar increased drinking.

View Article and Find Full Text PDF

Convergent Paired Electrolysis Enables Electrochemical Halogen-Atom Transfer-Mediated Alkyl Radical Cross-Coupling.

J Am Chem Soc

September 2025

Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China.

The direct cross-coupling of unactivated alkyl halides with aryl or heteroaryl partners remains a fundamental challenge in synthetic chemistry due to their inertness and propensity for side reactions. Herein, we report a transition-metal-free electrochemical halogen-atom transfer strategy that enables efficient alkyl radical cross-coupling via convergent paired electrolysis. In this system, anodically generated α-aminoalkyl radicals mediate the activation of alkyl iodides, while aryl/heteroaryl aldehydes or nitriles undergo cathodic reduction to afford persistent ketyl radical anions or aryl radical anions.

View Article and Find Full Text PDF

Substance misuse among college students continues to rise, with polysubstance use becoming increasingly common. Alcohol remains the most prevalent substance, with heavy episodic and high-quantity drinking linked to serious consequences, including injuries, assaults, and deaths. Concurrent use of alcohol and cannabis, as well as other illicit drugs, further compounds risks to health, safety, and academic functioning.

View Article and Find Full Text PDF

Background: This study examined motivational pathways between internalizing symptoms (i.e., depression, anxiety, stress) and simultaneous alcohol and cannabis use among young adults.

View Article and Find Full Text PDF