98%
921
2 minutes
20
Background: When selecting a manual wheelchair frame, the choice between rigid and folding frames carries significant implications. Traditional folding frames are expected to have more rolling resistance and power dissipation caused by frame deformation, while they are more convenient for transportation, such as in a car. A new hybrid frame, designed to be more rigid, aims to minimize power dissipation while still retaining foldability.
Aim: This study aimed to assess rolling resistance, power output, propulsion technique and physiological demands of handrim wheelchair propulsion across three different frames: a rigid frame, a hybrid frame and a conventional folding frame.
Materials And Methods: Forty-eight able-bodied participants performed coast-down tests using inertial measurement units to determine rolling resistance. Subsequently, four-minute submaximal exercise block under steady-state conditions at 1.11 m/s were performed on a wheelchair ergometer ( = 24) or treadmill ( = 24) to determine power output, propulsion technique and physiological demands.
Results: Repeated measures ANOVA revealed that the hybrid frame exhibited the lowest rolling resistance (7.0 ± 1.5N, ≤ 0.001) and required less power output (8.3 ± 1.0W, ≤ 0.001) at a given speed, compared to both the folding (9.3 ± 2.2N, 10.8 ± 1.4W) and rigid frame (8.0 ± 1.9N, 9.4 ± 1.6W). Subsequently, this resulted in significantly lower applied forces and push frequency for the hybrid frame. The folding frame had the highest energy expenditure (hybrid: 223 ± 44 W, rigid: 234 ± 51 W, folding: 240 ± 46 W, ≤ 0.001).
Conclusion: The hybrid frame demonstrated to be a biomechanically and physiologically beneficial solution compared to the folding frame, exhibiting lower rolling resistance, reduced power output, and consequently minimizing force application and push frequency, all while retaining its folding mechanism.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/17483107.2024.2365270 | DOI Listing |
J Rehabil Assist Technol Eng
September 2025
Department of Rehabilitation Science and Technology, University of Pittsburgh, Pittsburgh, PA, USA.
Minimizing repetitive strain (RS) is a key recommendation from clinical practice guidelines for preservation of upper limb. Propulsion force, which is required to overcome wheel rolling resistance (RR), is a major source of RS. A drum-based RR test method has been developed but has not been directly validated against propulsion forces.
View Article and Find Full Text PDFRSC Adv
September 2025
State Key Laboratory of Disaster Prevention & Reduction for Power Grid Changsha China
Positive temperature coefficient (PTC) materials are pivotal for safeguarding lithium iron phosphate batteries, yet their industrial application is hindered by critical drawbacks: excessive film thickness, high internal resistance, and poor solvent sustainability. Addressing these challenges, this study innovatively develops a solvent-free thermal rolling process to fabricate an asymmetric expansion polymer film, specifically thermoplastic polyurethane (TPU) reinforced polyethylene (PE)/carbon composites, which significantly enhances the PTC effect. The core mechanism lies in the asymmetric thermal expansion of TPU and PE: this unique behavior disrupts the conductive carbon network, triggering a sharp PTC transition at around 120 °C.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
September 2025
Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610065, China.
Detection methods with single-nucleotide specificity are essential tools for nucleic acid analysis in diverse clinical and biological settings. However, both hybridization-based and enzyme-based methods are only effective for discriminating single-nucleotide mutations at certain positions, making it difficult to detect nucleic acid targets having multiple nearby mutations. Herein, we describe the design of cooperative recognition probes (CRPs) that integrate both hybridization and ligation-based recognition mechanisms and thus are highly effective for discriminating mutations throughout all positions.
View Article and Find Full Text PDFBackground: Sotrovimab is a neutralising monoclonal antibody targeting the SARS-CoV-2 spike protein. We aimed to evaluate the efficacy and safety of sotrovimab in the RECOVERY trial, an investigator-initiated, individually randomised, controlled, open-label, adaptive platform trial testing treatments for patients admitted to hospital with COVID-19.
Methods: Patients admitted with COVID-19 pneumonia to 107 UK hospitals were randomly assigned (1:1) to either usual care alone or usual care plus a single 1 g infusion of sotrovimab, using web-based unstratified randomisation.
JAC Antimicrob Resist
April 2025
Department of Paediatric Infectious Diseases and Immunology, Southampton Children's Hospital, Southampton, UK.
Objectives: To improve antimicrobial stewardship (AMS) and reduce unnecessary antibiotic prescriptions in young children in a British primary care setting.
Methods: Forty-nine general practices in the South of England each hosted a 1 h in-house workshop, facilitated by trained local pharmacy professionals. This type of educational outreach approach using TARGET (Target Antibiotics Responsibly, Guidance, Education and Tools) antibiotic materials has previously been shown to reduce antibiotic dispensing in a UK primary care setting.