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Neutrophilic eccrine hidradenitis (NEH) is one of the cutaneous manifestations of chemotherapy side effects. However, it can arise from other non-chemotherapy medications. The granulocyte-colony-stimulating factor is a medication reported to trigger NEH.
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http://dx.doi.org/10.1002/ccr3.9114 | DOI Listing |
JAAD Case Rep
July 2025
Department of Dermatology, Department of Pathology, The University of Mississippi Medical Center, Associate Professor, Jackson, Mississippi.
J Cutan Pathol
May 2025
Dermatology Department, İstanbul Sultan 2 Abdülhamid Han Training and Research Hospital, İstanbul, Turkey.
The term "hidradenitis" designates diseases with inflammatory infiltrate around a sweat gland. Neutrophilic eccrine hidradenitis (NEH) is a reactive disorder usually induced by malignancy or chemotherapeutics, characterized by typically erythematous, edematous papules and plaques on the extremities, trunk, face, and palmar and plantar regions. In histopathology, dense neutrophilic infiltration around the eccrine gland can be seen.
View Article and Find Full Text PDFJ Cutan Pathol
April 2025
Division of Dermatology, The University of Texas at Austin, Dell Medical School, Austin, Texas, USA.
Pemetrexed is a chemotherapeutic, antimetabolite agent that has been used in oncology to treat diseases such as metastatic non-small cell lung cancer and unresectable malignant pleural mesothelioma. Pemetrexed use may result in pseudocellulitis, which presents as poorly demarcated patches or plaques with erythema, edema, warmth, and tenderness. These lesions can present unilaterally or bilaterally on the lower extremities.
View Article and Find Full Text PDFInt J Dermatol
April 2025
Department of Dermatology, Hospital Universitario Ramon y Cajal, IRYCIS, Universidad de Alcalá, Madrid, Spain.
Neutrophilic eccrine hidradenitis (NEH) is one of the cutaneous manifestations of chemotherapy side effects. However, it can arise from other non-chemotherapy medications. The granulocyte-colony-stimulating factor is a medication reported to trigger NEH.
View Article and Find Full Text PDF