Performance of high-dose omalizumab in chronic urticaria is predicted by initial improvement to standard dose.

J Allergy Clin Immunol Pract

Urticaria Centre of Excellence and Reference (UCARE), Department of Dermatology/Allergology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.

Published: November 2024


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaip.2024.06.014DOI Listing

Publication Analysis

Top Keywords

performance high-dose
4
high-dose omalizumab
4
omalizumab chronic
4
chronic urticaria
4
urticaria predicted
4
predicted initial
4
initial improvement
4
improvement standard
4
standard dose
4
performance
1

Similar Publications

The EBMT recommends rabbit anti-thymocyte or anti-T-lymphocyte globulin (rATG/ATLG) as GVHD prophylaxis in matched sibling donor (MSD) allogeneic hematopoietic cell transplantation (allo-HCT). However, discrepancies between recommendations and clinical practice were reflected in the EBMT survey. Therefore, we performed retrospective EBMT registry analysis from 2014 to 2021 to reinforce the real-world evidence context of rATG/ATLG impact on post-transplantation outcomes.

View Article and Find Full Text PDF

Staged Gamma Knife radiosurgery for large brain metastases: Local control and the influence of systemic treatment.

Radiother Oncol

September 2025

Amsterdam UMC, Location University of Amsterdam, Department of Neurosurgery, Meibergdreef 9, Amsterdam, the Netherlands; Amsterdam Neuroscience, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands.

Background And Purpose: Staged Gamma Knife radiosurgery (SGKRS) delivers high-dose radiotherapy to large brain metastases (BM) in two or three fractions with a time interval of several weeks. Various systemic treatments have also demonstrated favorable intracranial responses. Therefore, the outcome of patients undergoing radiosurgery and systemic treatment for large BM is of high interest but unknown.

View Article and Find Full Text PDF

Background: Sterile pyuria is a common manifestation of Kawasaki disease (KD). We investigated the characteristics of KD patients with sterile pyuria.

Methods: This retrospective study included 345 KD patients who had not received antimicrobial therapy before the diagnosis.

View Article and Find Full Text PDF

Objective: This study aims to evaluate the role of MRI-guided hysteroscopic one-step precise resection in diagnosing suspected myometrial invasion (MI) of endometrial cancer (EC) in patients desiring fertility preservation and to analyze the impact of suspected MI on the outcomes of fertility-preserving treatments.

Methods: A total of 169 patients with early-stage endometrial cancer who required fertility preservation were enrolled. Among them, 103 cases were ruled out for myometrial invasion by MRI (control group), while 66 cases exhibited suspected myometrial invasion.

View Article and Find Full Text PDF

Evaluating the Oncologic and Safety Outcomes of High-Dose Palliative Radiation Treatment with 30 Grays in Five Fractions.

Cureus

August 2025

Division of Radiation Oncology and Developmental Radiotherapeutics, BC Cancer - Vancouver, Vancouver, CAN.

Introduction In select tumor sites, symptom palliation and local control can be improved through delivering higher biological equivalent doses (BED) of radiotherapy. However, not all patients are suitable candidates for stereotactic body radiation therapy (SBRT). The 30 Grays in five fractions (30/5) regimen is a conformal, hypofractionated regimen that offers a higher BED compared to conventional palliative radiotherapy.

View Article and Find Full Text PDF