Article Synopsis
- Pretreatment helped reduce infections in mice by positively affecting their gut microbiota.
- It significantly increased levels of intestinal linoleic acid, which plays a role in gut health.
- Linoleic acid enhanced the intestinal barrier and minimized pathogen movement by influencing specific cellular pathways related to inflammation and gut function.
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Article Abstract
pretreatment mitigated infection in mice. improved gut microbiota disturbed by infection and significantly increased the level of intestinal linoleic acid in mice. Linoleic acid strengthened the intestinal epithelial barrier and reduced pathogen translocation partly by regulating NF-κB/MLCK pathway in a GPR40-dependent manner.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11183177 | PMC |
| http://dx.doi.org/10.1002/imt2.196 | DOI Listing |
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