Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Aims: Superior vena cava (SVC) isolation during atrial fibrillation catheter ablation is limited by the risk of collateral damage to the sinus node and/or the phrenic nerve. Due to its tissue-specificity, we hypothesized the feasibility and safety of pulsed-field ablation (PFA)-based SVC isolation.
Methods And Results: One hundred and five consecutive patients undergoing PFA-based AF catheter ablation were prospectively included. After pulmonary vein isolation (±posterior wall isolation and electrical cardioversion), SVC isolation was performed using a standardized workflow. Acute SVC isolation was achieved in 105/105 (100%) patients after 6 ± 1 applications. Transient phrenic nerve stunning occurred in 67/105 (64%) patients but without phrenic nerve palsy at the end of the procedure and at hospital discharge. Transient high-degree sinus node dysfunction occurred in 5/105 (4.7%) patients, with no recurrence at the end of the procedure and until discharge. At the 3-month follow-up visit, no complication occurred.
Conclusion: SVC isolation using a pentaspline PFA catheter is feasible and safe.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11252500 | PMC |
| http://dx.doi.org/10.1093/europace/euae160 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pulmonary Vein Isolation With or Without Empiric Superior Vena Cava Isolation in Patients Undergoing Ablation for Paroxysmal Atrial Fibrillation: The Randomized ESVCI-AF Trial.
Europace
August 2025
Department of Cardiovascular Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University.
Aims: The superior vena cava (SVC) has been implicated as a non-pulmonary vein trigger in the initiation and maintenance of atrial fibrillation (AF). However, the incremental benefit of empiric SVC isolation (SVCI) in addition to pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) remains inconclusive. This study aimed to determine whether adding empiric SVCI to PVI improves freedom from atrial arrhythmia (ATA) recurrence in patients with PAF.
View Article and Find Full Text PDFBackground: Superior vena cava (SVC)-right atrium (RA) spontaneous conduction block occurs in some patients. We demonstrated a novel approach for SVC isolation using visualization of the SVC-RA conduction block line as a white line with the extended early meets-late (EEML) tool of the CARTO system. The long-term durability of SVC isolation using white line has not been investigated.
View Article and Find Full Text PDFIsolated Right Chylothorax Secondary to Superior Vena Cava (SVC) Obstruction Successfully Treated With Endovascular Stenting.
Cureus
June 2025
Department of Pulmonology, All India Institute of Medical Sciences, Mangalagiri, Mangalagiri, IND.
Chylothorax, an uncommon cause of pleural effusion, typically results from thoracic duct injury or obstruction. Superior vena cava (SVC) obstruction is a rare etiology, often leading to right-sided chylothorax due to disrupted lymphatic drainage. This case report describes a 70-year-old female patient with a history of breast carcinoma who presented with right-sided chylothorax secondary to SVC thrombosis caused by a neglected chemoport.
View Article and Find Full Text PDFFeasibility, Acute Efficacy and Safety of Empirical Superior Vena Cava Isolation in Addition to Pulmonary Vein Isolation Using the Fourth-Generation Cryoballoon: Insights from a Randomized Trial.
J Clin Med
June 2025
Department of Cardiovascular Diseases, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Pulmonary vein isolation (PVI) is the standard treatment for atrial fibrillation (AF), but medium-term success rates remain suboptimal. Non-pulmonary vein triggers, particularly from the superior vena cava (SVC), contribute to AF recurrence. Empirical SVC isolation (SVCi) in addition to standard PVI may improve outcomes.
View Article and Find Full Text PDF