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This paper is concerned with the PDE (partial differential equation) and numerical analysis of a modified one-dimensional intravascular stent model. It is proved that the modified model has a unique weak solution by using the Galerkin method combined with a compactness argument. A semi-discrete finite-element method and a fully discrete scheme using the Euler time-stepping have been formulated for the PDE model. Optimal order error estimates in the energy norm are proved for both schemes. Numerical results are presented, along with comparisons between different decoupling strategies and time-stepping schemes. Lastly, extensions of the model and its PDE and numerical analysis results to the two-dimensional case are also briefly discussed.
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http://dx.doi.org/10.3934/mbe.2024248 | DOI Listing |
Front Oncol
August 2025
Department of Neurosurgery, Tengzhou Central People's Hospital, Tengzhou, Shandong, China.
Background: The objective of this study is to investigate the predictive role of O6-methylguanine-DNA methyltransferase (MGMT) and isocitrate dehydrogenase (IDH) status on the efficacy of bevacizumab (BEV) in high-grade glioma (HGG), while excluding the interference of chemotherapy agents.
Methods: A retrospective, single-center analysis was conducted on 103 patients with HGG who received BEV treatment. The enrolled patients were grouped based on their different biomarker statuses.
Front Public Health
September 2025
Department of Economics and Management, Jiangsu College of Administration, Nanjing, China.
This study utilizes data from the China Cancer Registry Annual Report and the "Qichacha" database to construct a time-region regression model based on panel data, aiming to explore the impact of polluting enterprises on regional cancer incidence rates between 2000 and 2008. The empirical analysis reveals that polluting enterprises significantly increase cancer incidence rates among both male and female populations, with a particularly marked effect on lung cancer. Heterogeneity analysis shows that the effect is most pronounced in the eastern and coastal regions, followed by the central and northeastern areas, with minimal impact in the western and inland regions.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
September 2025
Department of Internal Medicine, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Introduction: Anti-thyroid peroxidase antibodies (TPO-Ab) are detectable in almost all patients with autoimmune thyroid disease or Hashimoto's thyroiditis (HT) but may also be present in healthy individuals. HT affects women to a greater extent than men and can lead to overt hypothyroidism, which may increase the risk of miscarriage. There are no local data available on the prevalence of TPO-Ab among healthy women in the United Arab Emirates.
View Article and Find Full Text PDFInquiry
September 2025
Rice University, Houston, TX, USA.
To evaluate changes in enrollment, average risk scores, and premiums in the Affordable Care Act individual market after states transitioned from the federally facilitated marketplace (Healthcare.gov) to a state-based marketplace (SBM) between 2018 and 2023. This study employed a retrospective, quasi-experimental design of secondary data using a synthetic difference-in-differences analysis methodology.
View Article and Find Full Text PDFEmerg Med Australas
October 2025
Emergency Medicine Physician, Emergency Department, Instituto Neurologico de Colombia, Medellin, Colombia.
Objectives: To estimate the proportion of Emergency Department (ED) headache patients without neurological features who are diagnosed with a serious secondary headache cause.
Methods: Unplanned secondary analysis of HEAD Study/HEAD Colombia data. Patients without a known history of cerebral conditions and with a normal neurological assessment were included.